Tohoku Medical Megabank Brain Magnetic Resonance Imaging Study : rationale, design, and background

• 資料種別: 記事
• タイトル: Tohoku Medical Megabank Brain Magnetic Resonance Imaging Study : rationale, design, and background
• 著者・編者: Makiko Taira; Shunji Mugikura; Naoko Mori; Atsushi Hozawa; Tomo Saito; Tomohiro Nakamura; Hideyasu Kiyomoto; Tadao Kobayashi; Soichi Ogishima; Fuji Nagami; Akira Uruno; Ritsuko Shimizu; Tomoko Kobayashi; Jun Yasuda; Shigeo Kure; Miyuki Sakurai; Ikuko N. Motoike; Kazuki Kumada; Naoki Nakaya; Taku Obara; Kentaro Oba; Atsushi Sekiguchi; Benjamin Thyreau; Tatsushi Mutoh; Yuji Takano; Mitsunari Abe; Norihide Maikusa; Yasuko Tatewaki; Yasuyuki Taki; Nobuo Yaegashi; Hiroaki Tomita; Kengo Kinoshita; Shinichi Kuriyama; Nobuo Fuse; Masayuki Yamamoto
• 出版事項: 日本 : Japan Medical Association
• 出版年月日等: 2023-07-14
• 出版年（W3CDTF）: 2023-07-14
• タイトル（掲載誌）: JMA Journal
• 巻号年月日等（掲載誌）: 6(3)
• 掲載巻: 6(3)
• ISSN（掲載誌）: 2433-3298
• ISSN-L（掲載誌）: 2433-328X
• 本文の言語コード: eng
• DOI: 10.31662/jmaj.2022-0220; https://doi.org/10.31662/jmaj.2022-0220
• 国立国会図書館永続的識別子: info:ndljp/pid/14495016; https://dl.ndl.go.jp/pid/14495016
• コレクション（共通）: 障害者向け資料
• コレクション（障害者向け資料：レベル1）: テキストデータ
• コレクション（個別）: 国立国会図書館デジタルコレクション > 電子書籍・電子雑誌 > その他; https://dl.ndl.go.jp/collections/B00035
• 収集根拠: インターネット資料収集保存事業（WARP）
• 受理日（W3CDTF）: 2025-10-21T09:04:40+09:00
• 保存日（W3CDTF）: 2024-09-26
• 記録形式（IMT）: application/pdf
• オンライン閲覧公開範囲: インターネット公開
• 遠隔複写可否（NDL）: 不可
• 掲載誌（URI）: https://warp.da.ndl.go.jp/info:ndljp/pid/13747952/www.jmaj.jp/detail.php?id=10.31662%2Fjmaj.2022-0220
• 掲載誌（国立国会図書館永続的識別子）: info:ndljp/pid/14495014; https://dl.ndl.go.jp/pid/14495014
• 連携機関・データベース: 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp

• 要約等: <p>The Tohoku Medical Megabank Brain Magnetic Resonance Imaging Study (TMM Brain MRI Study) was established to collect multimodal information through neuroimaging and neuropsychological assessments to evaluate the cognitive function and mental health of residents who experienced the Great East Japan Earthquake (GEJE) and associated tsunami. The study also aimed to promote advances in personalized healthcare and medicine related to mental health and cognitive function among the general population. We recruited participants for the first (baseline) survey starting in July 2014, enrolling individuals who were participating in either the TMM Community-Based Cohort Study (TMM CommCohort Study) or the TMM Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study). We collected multiple magnetic resonance imaging (MRI) sequences, including 3D T1-weighted sequences, magnetic resonance angiography (MRA), diffusion tensor imaging (DTI), pseudo-continuous arterial spin labeling (pCASL), and three-dimensional fluid-attenuated inversion recovery (FLAIR) sequences. To assess neuropsychological status, we used both questionnaire- and interview-based rating scales. The former assessments included the Tri-axial Coping Scale, Impact of Event Scale in Japanese, Profile of Mood States, and 15-item Depression, Anxiety, and Stress Scale, whereas the latter assessments included the Mini-Mental State Examination, Japanese version. A total of 12,164 individuals were recruited for the first (baseline) survey, including those unable to complete all assessments. In parallel, we returned the MRI results to the participants and subsequently shared the MRI data through the TMM Biobank. At present, the second (first follow-up) survey of the study started in October 2019 is underway. In this study, we established a large and comprehensive database that included robust neuroimaging data as well as psychological and cognitive assessment data. In combination with genomic and omics data already contained in the TMM Biobank database, these data could provide new insights into the relationships of pathological processes with neuropsychological disorders, including age-related cognitive impairment.</p>
• DOI: 10.31662/jmaj.2022-0220
• オンライン閲覧公開範囲: インターネット公開
• 連携機関・データベース: 科学技術振興機構 : J-STAGE; http://www.jstage.jst.go.jp

• 要約等: <p>The Tohoku Medical Megabank Brain Magnetic Resonance Imaging Study (TMM Brain MRI Study) was established to collect multimodal information through neuroimaging and neuropsychological assessments to evaluate the cognitive function and mental health of residents who experienced the Great East Japan Earthquake (GEJE) and associated tsunami. The study also aimed to promote advances in personalized healthcare and medicine related to mental health and cognitive function among the general population. We recruited participants for the first (baseline) survey starting in July 2014, enrolling individuals who were participating in either the TMM Community-Based Cohort Study (TMM CommCohort Study) or the TMM Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study). We collected multiple magnetic resonance imaging (MRI) sequences, including 3D T1-weighted sequences, magnetic resonance angiography (MRA), diffusion tensor imaging (DTI), pseudo-continuous arterial spin labeling (pCASL), and three-dimensional fluid-attenuated inversion recovery (FLAIR) sequences. To assess neuropsychological status, we used both questionnaire- and interview-based rating scales. The former assessments included the Tri-axial Coping Scale, Impact of Event Scale in Japanese, Profile of Mood States, and 15-item Depression, Anxiety, and Stress Scale, whereas the latter assessments included the Mini-Mental State Examination, Japanese version. A total of 12,164 individuals were recruited for the first (baseline) survey, including those unable to complete all assessments. In parallel, we returned the MRI results to the participants and subsequently shared the MRI data through the TMM Biobank. At present, the second (first follow-up) survey of the study started in October 2019 is underway. In this study, we established a large and comprehensive database that included robust neuroimaging data as well as psychological and cognitive assessment data. In combination with genomic and omics data already contained in the TMM Biobank database, these data could provide new insights into the relationships of pathological processes with neuropsychological disorders, including age-related cognitive impairment.</p>
• DOI: 10.31662/jmaj.2022-0220; https://doi.org/10.31662/jmaj.2022-0220
• オンライン閲覧公開範囲: インターネット公開
• 関連情報（URI）: http://id.ndl.go.jp/digimeta/14495016; https://dl.ndl.go.jp/pid/14495016; https://www.jmaj.jp/download.php?id=10.31662/jmaj.2022-0220; https://search.jamas.or.jp/link/ui/2024269065
• 参照: STAT image reporting in a large-scale cohort: types, frequency, and insights from the Tohoku Medical Megabank Brain MRI Study; https://cir.nii.ac.jp/crid/1360868136179827200; A Principal Component Analysis of Metabolome and Cognitive Decline Among Japanese Older Adults: Cross-sectional Analysis Using Tohoku Medical Megabank Cohort Study Data; https://cir.nii.ac.jp/crid/1390021293451248256; Language Registration-Based Scoring System for Handwritten Logical Memory of Wechsler Memory Scale-Revised: Developed and Validated in the Tohoku Medical Megabank Project; https://cir.nii.ac.jp/crid/1390024246556739328; skeletonized MDに基づくヒストグラム統計量と年齢との相関：東北メディカル・メガバンクにおける検討［大会長賞記録］; https://cir.nii.ac.jp/crid/1390026026771843968
• 参照: Faculty Opinions recommendation of De novo aneurysm formation and growth of untreated aneurysms: a 5-year MRA follow-up in a large cohort of patients with coiled aneurysms and review of the literature.; https://cir.nii.ac.jp/crid/1881428067611676544; Statistical parametric mapping of biomechanical one-dimensional data with Bayesian inference; https://cir.nii.ac.jp/crid/1883399490773143168
• 連携機関・データベース: 国立情報学研究所 : CiNii Research; https://cir.nii.ac.jp/
• 提供元機関・データベース: Japan Link Center; https://japanlinkcenter.org/top; 雑誌記事索引データベース; https://ndlsearch.ndl.go.jp; Crossref; https://www.crossref.org; 科学研究費助成事業データベース; https://kaken.nii.ac.jp/ja
• 書誌ID（NDLBibID）: 14495016; http://id.ndl.go.jp/bib/14495016