タイトル（掲載誌）International journal of urology
一般注記type:Thesis
OBJECTIVES:To evaluate how guidance on water-intake impacts the degree of nocturia.METHODS:A total of 67 male patients were enrolled in the present study. Patients were asked to adjust their water and food intakes so that their 24-h urine production/bodyweight would be equal or lower than 30 mL/kg. One month after the treatment, the therapeutic gain from and adverse effects of fluid restriction were examined by comparing the pretreatment and post-treatment value of various parameters.RESULTS:Overall, 65 eligible patients were evaluated. In 44 patients (67%), the frequency of nocturia was improved to one or more times. The change in frequency of nocturia showed a positive correlation with the change in nocturnal urine volume. The change in nocturnal urine volume showed a positive correlation with the changes in 24-h urine production/bodyweight, 24-h drinking volume and daytime drinking volume. The changes in 24-h urine production/bodyweight and daytime drinking volume were independent factors influencing therapeutic effect. None of the participants reported any adverse event.CONCLUSIONS:In patients with a 24-h urine production/bodyweight equal or higher than 30 mL/kg, guidance on water intake might be considered effective and safe as a lifestyle therapy. Water restriction should be carried out not only in the evening, but also during daytime.
博士（医学）・乙第1348号・平成26年12月3日
© 2014 The Japanese Urological Association
identifier:International journal of urology Vol.21 No.6 p.595-600
identifier:09198172
identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/2752
identifier:International journal of urology, 21(6): 595-600
DOIinfo:doi/10.1111/iju.12387
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