並列タイトル等Effect of mouth cleaning with hinokitiol-containing gel on oral malodor: a randomized, open-label pilot study
一般注記The aim of the study was to evaluate the effect of mouth cleaning with hinokitiol-containing gel on oral malodor.
An open-label, randomized, controlled trial was conducted to assess oral malodor and clinical parameters related to oral malodor before and after mouth cleaning with hinokitiol-containing gel (n=9) or with gel not including hinokitiol (n=9). Mouth cleaning included the teeth, gingiva, and tongue and was carried out 3 times per day for 4weeks.
Organoleptic test (OLT) scores (P=.021), levels of hydrogen sulfide (P=.008) and methyl mercaptan (P=.020), frequency of bleeding on probing, average probing pocket depth, and plaque index significantly improved in the group using hinokitiol. In contrast, only the OLT score (P=.031) significantly improved in the control group after the treatment regimen.
Mouth cleaning with hinokitiol-containing gel may be effective for reduction of oral malodor.
Oral Surg Oral Med Oral Pathol Oral Radiol. 2013 Oct;116(4):433-9. doi: 10.1016/j.oooo.2013.05.021. Epub 2013 Aug 19.
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