雑誌実験動物
Volume number42(4)
Article体外受精-培養-移植...

体外受精-培養-移植系の薬物の安全性試験への応用--抗癌剤投与雄マウスの受精能試験

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体外受精-培養-移植系の薬物の安全性試験への応用--抗癌剤投与雄マウスの受精能試験

Call No. (NDL)
Z19-425
Bibliographic ID of National Diet Library
3857455
Material type
記事
Author
上田 乙也 他
Publisher
東京 : 日本実験動物学会
Publication date
1993-10
Material Format
Digital
Journal name
実験動物 42(4) 1993.10
Publication Page
p.p565～570
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Detailed bibliographic record

Summary, etc.：

本試験では, 薬物の安全性試験, 特に雄に対する生殖発生毒性の評価系へのマウスの体外受精―培養―移植系の応用を試みた。DNA合成を阻害し, 抗癌作用をもつ白金錯化合物DWA 2114Rを被験物質とし, 10週齢の雄に75mg/kgを尾静脈内に単回投与した。投与後4, 5, 6週目に過排卵処理雌と行っ...

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Digital

Material Type
記事
Title
体外受精-培養-移植系の薬物の安全性試験への応用--抗癌剤投与雄マウスの受精能試験
Author/Editor
上田 乙也 他
Author Heading
上田 乙也
Periodical title
実験動物
No. or year of volume/issue
42(4) 1993.10
Volume
42
Issue
4
Pages
p565～570
Publication date of volume/issue (W3CDTF)
1993-10