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DNA損傷応答関連遺伝子の異常と悪性腫瘍・自己免疫疾患との関連について

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DNA損傷応答関連遺伝子の異常と悪性腫瘍・自己免疫疾患との関連について

Material type
記事
Author
兪 史幹ほか
Publisher
The Japan Society for Clinical Immunology
Publication date
2006
Material Format
Digital
Journal name
日臨免誌 29 3
Publication Page
p.136-147
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Summary, etc.:

生体を構成する細胞の遺伝情報の恒常性維持は,多彩かつ精緻に制御された諸生命活動に必須の細胞機能であり,その破綻は遺伝情報における変異の蓄積ならびにアポトーシス誘導機構の異常をもたらし,癌をはじめとする諸疾患の誘因となると考えられている.遺伝情報の維持において,DNA損傷応答機構,とりわけ細胞周期チェ...

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Digital

Material Type
記事
Publication Date
2006
Publication Date (W3CDTF)
2006
Periodical title
日臨免誌
No. or year of volume/issue
29 3
Volume
29
Issue
3
Pages
136-147