成人無菌性髄膜炎の臨床的検討 : 流行性と起因ウイルスの同定
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- Material Type
- 記事
- Author/Editor
- 竹島 慎一音成 秀一郎姫野 隆洋 他
- Alternative Title
- Clinical, epidemiological, and etiological studies of aseptic meningitis in adults
- Periodical title
- 臨床神経学 = Clinical neurology / 日本神経学会 編
- No. or year of volume/issue
- 54(10):2014.10
- Volume
- 54
- Issue
- 10
- Pages
- 791-797
- Publication date of volume/issue (W3CDTF)
- 2014-10
- ISSN (Periodical Title)
- 0009-918X
- ISSN-L (Periodical Title)
- 0009-918X
- Publication (Periodical Title)
- 東京 : 日本神経学会
- Place of Publication (Country Code)
- JP
- Text Language Code
- jpn
- Subject Heading
- NDLC
- Target Audience
- 一般
- Holding library
- 国立国会図書館
- Call No.
- Z19-298
- Data Provider (Database)
- 国立国会図書館 : 国立国会図書館雑誌記事索引
- Bibliographic ID (NDL)
- 025841835
- Bibliographic Record Category (NDL)
- 632
- Summary, etc.
- From summer to autumn, we noted the occurrence of a small epidemic of aseptic meningitis in adults. Over the last 10 years, we have encountered 203 male (mean age, 34.6 ± 15.0 years) and 157 female (mean age, 35.6 ± 16.3 years) patients with aseptic meningitis. We could identify the causative virus in 17 (81%) of 21 cases during the abovementioned months in 2012. Identification rates of the virus in the stool, cerebrospinal fluid, throat swab, and serum samples were 71%, 67%, 42%, and 5%, respectively. The etiological viruses included enteroviruses in all cases, such as echovirus type 9 (E9) in 9 cases, echovirus type 6 (E6) in 4 cases, coxsackievirus type A9 in 1 case, and unknown type of enterovirus in 3 cases. No differences in the clinical manifestations and laboratory findings were noted between E9 meningitis and E6 meningitis. In addition, we countered 14 cases of mumps meningitis, 7 cases of varicella-zoster virus meningitis and 6 cases of herpes simplex meningitis during the last 10 years; these cases did not occur as an epidemic, but occurred sporadically. Cases of mumps meningitis were noted in all seasons, and cases of varicella-zoster virus meningitis were only noted from summer to winter. The etiology of epidemic aseptic meningitis in adults could be mainly due to enterovirus infection, and its prognosis was benign.10年間で成人無菌性髄膜炎，男性203例，女性157例を経験した．毎年夏～秋に，数回の小流行をみとめた．2012年流行期の21例中17例（81％）で起因ウイルスを同定した．試料の同定率は，便71％，髄液67％，咽頭拭い液42％，血清5％であった．すべてエンテロウイルスで，エコーウイルス（E）9型9例，E6型4例，コクサキーA9型1例，3例はエンテロウイルス属まで同定できた．E9型とE6型の臨床的差異はなかった．10年間でムンプス髄膜炎14例，水痘・帯状疱疹ウイルス髄膜炎8例，単純ヘルペスウイルス髄膜炎5例をみとめたが，散発的発症であった．流行性のものはエンテロウイルスが主であり良好な経過であった．
- DOI
- 10.5692/clinicalneurol.54.791
- Access Restrictions
- インターネット公開
- Data Provider (Database)
- 科学技術振興機構 : J-STAGE
- Summary, etc.
- 10年間で成人無菌性髄膜炎，男性203例，女性157例を経験した．毎年夏～秋に，数回の小流行をみとめた．2012年流行期の21例中17例（81％）で起因ウイルスを同定した．試料の同定率は，便71％，髄液67％，咽頭拭い液42％，血清5％であった．すべてエンテロウイルスで，エコーウイルス（E）9型9例，E6型4例，コクサキーA9型1例，3例はエンテロウイルス属まで同定できた．E9型とE6型の臨床的差異はなかった．10年間でムンプス髄膜炎14例，水痘・帯状疱疹ウイルス髄膜炎8例，単純ヘルペスウイルス髄膜炎5例をみとめたが，散発的発症であった．流行性のものはエンテロウイルスが主であり良好な経過であった．
- DOI
- 10.5692/clinicalneurol.54.791
- Related Material (URI)
- References
- Etiology of aseptic meningitis and encephalitis in an adult populationASEPTIC MENINGITIS AND VIRAL MENINGITISEpidemiology of herpes zoster and its relationship to varicella in Japan: A 10‐year survey of 48,388 herpes zoster cases in Miyazaki prefectureMolecular Evolution of Human Echovirus 9 Isolated from Patients with Aseptic Meningitis in Northern Kyushu during the Summer of 1997ENTEROVIRUSES AND PARECHOVIRUSESAseptic meningitis and encephalitis because of herpesviruses and enteroviruses in an immunocompetent adult populationOutbreak of Aseptic Meningitis due to ECHO-9 in Northern Kyushu Island in the Summer of 1997.
- Data Provider (Database)
- 国立情報学研究所 : CiNii Research
- Original Data Provider (Database)
- Japan Link Center雑誌記事索引データベースCrossrefPubMedCiNii Articles
- Bibliographic ID (NDL)
- 025841835
- NAID
- 130004700493