非ペプチド性経口RXFP1作動薬AZD5462の創製

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Summary, etc.：: <p>RXFP1（Relaxin family peptide receptor 1）作動薬は、心不全・腎不全など、幅広い疾患への治療効果が期待されている。実際に、RXFP1の内因性ペプチドリガンドrelaxin-2の遺伝子組み換え製剤であるserelaxinが、急性心不全などを適応症として臨床試験...

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Material Type: 記事
Title: 非ペプチド性経口RXFP1作動薬AZD5462の創製
Author Heading: 淵上龍一
坂槇茂輝
丹羽靖哉
Lars Granberg Kenneth
Publication Date: 2024-08-01
Publication Date (W3CDTF): 2024-08-01
Periodical title: MEDCHEM NEWS
No. or year of volume/issue: 34 3
Volume: 34
Issue: 3
Pages: 155-159
Publication date of volume/issue (W3CDTF): 2024-08-01
ISSN (Periodical Title): 24328618
ISSN-L (Periodical Title): 24328618
Publication (Periodical Title): The Pharmaceutical Society of Japan
Text Language Code: ja
Subject Heading: AZD5462
RXFP1
relaxin-2
heart failure
small molecule
Target Audience: 一般
DOI: 10.14894/medchem.34.3_155
https://doi.org/10.14894/medchem.34.3_155
Data Provider (Database): 国立情報学研究所 : CiNii Research
https://cir.nii.ac.jp/
Original Data Provider (Database): Japan Link Center
https://japanlinkcenter.org/top