神経伝達物質放出を制御するシンタキシン1の二つの顔 : STX1AとSTX1Bの機能的差異と病態生理学的意義

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Summary, etc.：: <p>シンタキシン1（STX1）は神経伝達物質放出を制御するSNAREタンパク質であり，STX1AとSTX1Bの2つのアイソフォームを持つ。遺伝子改変マウスを用いた研究から，STX1Aはモノアミン系シナプス伝達，STX1Bは神経細胞の生存維持やGABA作動性シナプスの制御に重要であり，その機能破綻が...

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Material Type: 記事
Title: 神経伝達物質放出を制御するシンタキシン1の二つの顔 : STX1AとSTX1Bの機能的差異と病態生理学的意義
Author Heading: 三嶋竜弥
Publication Date: 2025-03-31
Publication Date (W3CDTF): 2025-03-31
Periodical title: 杏林医会誌
No. or year of volume/issue: 56 1
Volume: 56
Issue: 1
Pages: 33-37
Publication date of volume/issue (W3CDTF): 2025-03-31
ISSN (Periodical Title): 03685829
ISSN-L (Periodical Title): 03685829
Publication (Periodical Title): The Kyorin Medical Society
Text Language Code: ja
Target Audience: 一般
DOI: 10.11434/kyorinmed.56.33
https://doi.org/10.11434/kyorinmed.56.33
Data Provider (Database): 国立情報学研究所 : CiNii Research
https://cir.nii.ac.jp/
Original Data Provider (Database): Japan Link Center
https://japanlinkcenter.org/top