A comprehensive review on the chromatin conformation change code (4C) theory: A theory on ways of higher eukaryotes to gain un-programmed and new cell functions by means of irreversible creation of chromatin structure plasticity with epigenetic modifications through numerous generations

• Material Type: 文書・図像類
• Title: A comprehensive review on the chromatin conformation change code (4C) theory: A theory on ways of higher eukaryotes to gain un-programmed and new cell functions by means of irreversible creation of chromatin structure plasticity with epigenetic modifications through numerous generations
• Author/Editor: 中山, 建男; 中山, 雅美; Nakayama, Tatsuno
• Author Heading: 中山, 建男 ナカヤマ, タツオ; 中山, 雅美 ナカヤマ, マサミ; Nakayama, Tatsuno
• Publication, Distribution, etc.: Research Trends
• Publication Date: 2021
• Publication Date (W3CDTF): 2021
• Periodical title: Current Topics in Biochemical Research
• No. or year of volume/issue: 22
• Volume: 22
• Pages: 43-90
• ISSN (Periodical Title): ISSN : 0972-4583
• Text Language Code: eng
• Subject Heading: gene targeting techniques; histone deacetylase2-deficient DT40 mutants; numerous generations during continuous cultivation; decreases in immunoglobulin mRNA/protein levels; changes in mRNA levels of transcription factors; epigenetic modification; chromatin structure plasticity; gain of un-programmed and new cell functions; chromatin conformation change code theory
• Target Audience: 一般
• Note (General): application/pdf
• Access Restrictions: 限定公開
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 宮崎大学 : 宮崎大学学術情報リポジトリ

• Summary, etc.: In this article we first reviewed our studies on the exclusion of a large amount of IgM H- and L-chains excessively accumulated in histone deacetylase...