Immunohistochemical study of thyroid transcription factor-1 and surfactant-associated protein A for investigation of peripheral airway structure in perinatal fatality

Material type: 文書・図像類

Author: SHIMADA, Ichirohほか

Publisher: Elsevier B.V.

Publication date: 2008-03

Material Format: Digital

Capacity, size, etc.: -

NDC: -

View All

Notes on use

Note (General)：: We studied histopathological findings of the lungs in four cases where there was a suspicion of infanticide whereby an autopsy was performed. All four...

Search by Bookstore

Holdings of Libraries in Japan

This page shows libraries in Japan other than the National Diet Library that hold the material.

List of Cooperating Institutions and Databases

Please contact your local library for information on how to use materials or whether it is possible to request materials from the holding libraries.

other

Ｕｎｉｖｅｒｓｉｔｙ　ｏｆ　Ｆｕｋｕｉ　Ａｃａｄｅｍｉｃ　Ｒｅｐｏｓｉｔｏｒｙ
Digital
You can check the holdings of institutions and databases with which 学術機関リポジトリデータベース（IRDB）（機関リポジトリ） is linked at the site of 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）.
Ｕｎｉｖｅｒｓｉｔｙ　ｏｆ　Ｆｕｋｕｉ　Ａｃａｄｅｍｉｃ　Ｒｅｐｏｓｉｔｏｒｙ

Search by Bookstore

Bibliographic Record

You can check the details of this material, its authority (keywords that refer to materials on the same subject, author's name, etc.), etc.

Digital

Material Type: 文書・図像類
Title: Immunohistochemical study of thyroid transcription factor-1 and surfactant-associated protein A for investigation of peripheral airway structure in perinatal fatality
Author/Editor: SHIMADA, Ichiroh
MATSUI, Kazuhiro
KOMINATO, Yoshihiko
HATA, Yukiko
TAKIZAWA, Hisao
NISHIDA, Naoki
Author Heading: SHIMADA, Ichiroh
MATSUI, Kazuhiro
KOMINATO, Yoshihiko
HATA, Yukiko
TAKIZAWA, Hisao
NISHIDA, Naoki
Publication, Distribution, etc.: Elsevier B.V.
Publication Date: 2008-03
Publication Date (W3CDTF): 2008-03
Periodical title: Legal Medicine
No. or year of volume/issue: 10 2
Volume: 10
Issue: 2
Pages: 96-100
ISSN (Periodical Title): ISSN : 1344-6223
Text Language Code: eng
Subject Heading: Perinatal fatality
Peripheral airway structure
Immunohistochemistry
Anti- thyroid transcription factor-1
Anti- surfactant-associated protein A
Target Audience: 一般
Note (General): We studied histopathological findings of the lungs in four cases where there was a suspicion of infanticide whereby an autopsy was performed. All four babies were born in full term delivery. It was difficult to discern whether the peripheral airways of the lungs were open or closed with conventional histological examination. Therefore immunohistochemistry with a combination of anti- thyroid transcription factor-1 (TTF-1) and anti- surfactant-associated protein A (PE-10) was used in order to elucidate the fundamental structures of the peripheral airways. TTF-1 highlighted nuclei of Clara cells and type II alveolar cells. The findings of immunohistochemistry with TTF-1 enabled us to more objectively recognize the peripheral airways: respiratory bronchioles and alveolar ducts, even in collapsed lungs. PE-10 was expressed in the cytoplasm of Clara cells, type II alveolar cells, and the substance of air space. Aspect for immunohistochemistry with PE-10 appeared to be granular in closed air space, whereas it appeared to be stretched membranously along the interalveolar septa in open air space. These findings suggest that application of immunohistochemistry with TTF-1 and PE-10 is a useful diagnostic tool in judging perinatal fatality.
Source: https://u-fukui.repo.nii.ac.jp/?action=repository_action_common_download&item_id=19922&item_no=1&attribute_id=22&file_no=1
https://u-fukui.repo.nii.ac.jp/?action=repository_action_common_download&item_id=19922&item_no=1&attribute_id=22&file_no=1
Access Restrictions: 限定公開
Related Material (DOI): 10.1016/j.legalmed.2007.08.004
Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）
https://irdb.nii.ac.jp
Original Data Provider (Database): 福井大学 : 福井大学学術機関リポジトリ