Biotin and carnitine deficiency due to hypoallergenic formula nutrition in infants with milk allergy

• Material Type: 文書・図像類
• Title: Biotin and carnitine deficiency due to hypoallergenic formula nutrition in infants with milk allergy
• Author/Editor: Hayashi, Hisako; Tokuriki, Shuko; Okuno, Takashi; Shigematsu, Yosuke; Akiba, Yasushi; Matsuyama, Go; Sawada, Ken; Ohshima, Yusei
• Author Heading: Hayashi, Hisako; Tokuriki, Shuko; Okuno, Takashi; Shigematsu, Yosuke; Akiba, Yasushi; Matsuyama, Go; Sawada, Ken; Ohshima, Yusei
• Publication, Distribution, etc.: Wiley Blackwell
• Publication Date: 2014-04
• Publication Date (W3CDTF): 2014-04
• Periodical title: Pediatrics International
• No. or year of volume/issue: 56 2
• Volume: 56
• Issue: 2
• Pages: 286-288
• ISSN (Periodical Title): ISSN : 1328-8067
• Text Language Code: eng
• Subject Heading: amino acid formula; biotin deficiency; camitine deficiency; milk allergy
• Target Audience: 一般
• Note (General): Amino acid formulas and hydrolyzed formulas given to infants in Japan with milk allergies theoretically contain little, if any, biotin and carnitine. We assessed biotin and carnitine insufficiency in six infants with milk allergy who were fed amino acid formulas and/or hydrolyzed formulas, by measuring urine 3-hydroxyisovaleric acid (3- HIA) and serum free carnitine ( C0), respectively. All patients presented with elevated urine 3- HIA and lowered serum C0 compared with post-menstrual age-matched infants who were fed breast milk or standard infant formulas. Supplementation with biotin and l-carnitine immediately improved the insufficiency. Care should be taken to avoid biotin and carnitine deficiency in allergic infants fed amino acid or hydrolyzed formulas.
• Access Restrictions: 限定公開
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 福井大学 : 福井大学学術機関リポジトリ

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