A dynein-associated photoreceptor protein prevents ciliary acclimation to blue light

• Material Type: 文書・図像類
• Title: A dynein-associated photoreceptor protein prevents ciliary acclimation to blue light
• Author/Editor: Kutomi, Osamu; Yamamoto, Ryosuke; Hirose, Keiko; Mizuno, Katsutoshi; Nakagiri, Yuuhei; Imai, Hiroshi; Noga, Akira; Obbineni, Jagan Mohan; Zimmermann, Noemi; Nakajima, Masako; Shibata, Daisuke; Shibata, Misa; Shiba, Kogiku; Kita, Masaki; Kigoshi, Hideo; Tanaka, Yui; Yamasaki, Yuya; Asahina, Yuma; Song, Chihong; Nomura, Mami; Nomura, Mamoru; Nakajima, Ayako; Nakachi, Mia; Yamada, Lixy; Nakazawa, Shiori; Sawada, Hitoshi; Murata, Kazuyoshi; Mitsuoka, Kaoru; Ishikawa, Takashi; Wakabayashi, Ken-ichi; Kon, Takahide; Inaba, Kazuo
• Author Heading: Kutomi, Osamu; Yamamoto, Ryosuke; Hirose, Keiko; Mizuno, Katsutoshi; Nakagiri, Yuuhei; Imai, Hiroshi; Noga, Akira; Obbineni, Jagan Mohan; Zimmermann, Noemi; Nakajima, Masako; Shibata, Daisuke; Shibata, Misa; Shiba, Kogiku; Kita, Masaki; Kigoshi, Hideo; Tanaka, Yui; Yamasaki, Yuya; Asahina, Yuma; Song, Chihong; Nomura, Mami; Nomura, Mamoru; Nakajima, Ayako; Nakachi, Mia; Yamada, Lixy; Nakazawa, Shiori; Sawada, Hitoshi; Murata, Kazuyoshi; Mitsuoka, Kaoru; Ishikawa, Takashi; Wakabayashi, Ken-ichi; Kon, Takahide; Inaba, Kazuo
• Publication, Distribution, etc.: the American Association for the Advancement of Science
• Publication Date: 2021-02-26
• Publication Date (W3CDTF): 2021-02-26
• Alternative Title: A dynein-associated photoreceptor protein prevents ciliary acclimation to blue light
• Periodical title: SCIENCE ADVANCES
• No. or year of volume/issue: 7 9
• Volume: 7
• Issue: 9
• Pages: 1-13
• ISSN (Periodical Title): ISSN : 2375-2548
• Text Language Code: eng
• Target Audience: 一般
• Note (General): Light-responsive regulation of ciliary motility is known to be conducted through modulation of dyneins, but the mechanism is not fully understood. Here, we report a novel subunit of the two-headed f/I1 inner arm dynein, named DYBLUP, in animal spermatozoa and a unicellular green alga. This subunit contains a BLUF (sensors of blue light using FAD) domain that appears to directly modulate dynein activity in response to light. DYBLUP (dynein-associated BLUF protein) mediates the connection between the f/I1 motor domain and the tether complex that links the motor to the doublet microtubule. Chlamydomonas lacking the DYBLUP ortholog shows both positive and negative phototaxis but becomes acclimated and attracted to high-intensity blue light. These results suggest a mechanism to avoid toxic strong light via direct photoregulation of dyneins.; source:https://www.science.org/doi/10.1126/sciadv.abf3621
• Source: https://u-fukui.repo.nii.ac.jp/?action=repository_action_common_download&item_id=29369&item_no=1&attribute_id=22&file_no=1
• Access Restrictions: 限定公開
• Rights (production): CC BY-NC
• Related Material (DOI): 10.1126/sciadv.abf362
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 福井大学 : 福井大学学術機関リポジトリ