Comparison of Brain Tumor Contrast-enhancement on T1-CUBE and 3D-SPGR Images

• Material Type: 博士論文
• Title: Comparison of Brain Tumor Contrast-enhancement on T1-CUBE and 3D-SPGR Images
• Author/Editor: Mungunkhuyag, Majigsuren; Abe, Takashi; Kageji, Teruyoshi; Matsuzaki, Kenji; Takeuchi, Mayumi; Iwamoto, Seiji; Otomi, Yoichi; Uyama, Naoto; Nagahiro, Shinji; Harada, Masafumi
• Author Heading: Mungunkhuyag, Majigsuren; Abe, Takashi; Kageji, Teruyoshi; Matsuzaki, Kenji; Takeuchi, Mayumi; Iwamoto, Seiji; Otomi, Yoichi; Uyama, Naoto; Nagahiro, Shinji; Harada, Masafumi
• Publication, Distribution, etc.: Japanese Society for Magnetic Resonance in Medicine
• Publication Date: 2016-01-01
• Publication Date (W3CDTF): 2016-01-01
• Alternative Title: T1-CUBE法と3D-SPGR法による脳腫瘍造影増強効果の比較; Brain Tumor CE on T1-Cube versus 3D SPGR
• Periodical title: Magnetic Resonance in Medical Sciences
• No. or year of volume/issue: 15 1
• Volume: 15
• Issue: 1
• Pages: 34-40
• ISSN (Periodical Title): ISSN : 1880-2206; ISSN : 1347-3182
• Degree grantor/type: 徳島大学
• Date Granted: 2015-05-28
• Dissertation Number: 甲第2855号
• Degree Type: 博士（医学）
• Text Language Code: eng
• Subject Heading: 三次元 fast spoiled gradient recall acquisition in steady state (3D FSPGR); 脳腫瘍; 造影磁気共鳴画像; T1-Cube シーケンス; brain tumor; contrast-enhanced magnetic resonance imaging (CE MRI); T1-Cube sequence; 3-dimensional fast spoiled gradient recall acquisition in steady state (3D FSPGR)
• Target Audience: 一般
• Note (General): Purpose: T1-Cube (GE HealthCare) is a relatively new 3-dimensional (3D) fast spin-echo (FSE)-based magnetic resonance (MR) imaging sequence that uses a variable flip angle to acquire gap-free volume scans. We compared the gadolinium enhancement characteristics of a heterogeneous population of brain tumors imaged by T1-Cube and then 3D fast spoiled gradient recall acquisition in steady state (3D FSPGR) 3-tesla MR imaging to identify the superior modality for specific diagnostic purposes. Methods: We examined 61 lesions from 32 patients using the 2 sequences after administration of gadopentetic acid (Gd-DTPA; 0.1 mmol/kg). Two neuroradiologists independently measured each lesion twice using a region-of-interest (ROI) method. We measured the contrast-to-noise ratio (CNR), the difference in signal intensity (SI) between the tumor and normal white matter relative to the standard deviation (SD) of the SI within the lesion, for both post-contrast 3D FSPGR and post-contrast T1-Cube images of the same tumor and compared modality-specific CNRs for all tumors and in subgroups defined by tumor size, enhancement ratio, and histopathology. Results: The mean CNR was significantly higher on T1-Cube images than 3D FSPGR images for the total tumor population (1.85 ± 0.97 versus 1.12 ± 1.05, P < 0.01) and the histologic types, i.e., metastasis (P < 0.01) and lymphoma (P < 0.05). The difference in CNR was even larger for smaller tumors in the metastatic group (4.95 to 23.5 mm2) (P < 0.01). In contrast, mean CNRs did not differ between modalities for high grade glioma and meningioma. Conclusions: Gadolinium enhancement of brain tumors was generally higher when imaged by T1-Cube than 3D FSPGR, and T1-Cube with Gd enhancement may be superior to 3D FSPGR for detecting smaller metastatic tumors.
• Format (IMT): application/pdf
• Access Restrictions: インターネット公開
• Related Material (DOI): 10.2463/mrms.2014-0129
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 徳島大学 : 徳島大学機関リポジトリ

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http://repo.lib.tokushima-u.ac.jp/files/public/10/109458/20170929144034712676/LID201506251002.pdf fulltext

http://repo.lib.tokushima-u.ac.jp/files/public/10/109458/2017092914403527312/LID201601251001.pdf fulltext