Influential factors on serum albumin concentration in hospitalized chronic kidney disease patients

• Material Type: 博士論文
• Title: Influential factors on serum albumin concentration in hospitalized chronic kidney disease patients
• Author/Editor: Yoshimoto, Sakiya; Nagai, Kojiro; Shibata, Eriko; Ueda, Sayo; Ono, Hiroyuki; Tamaki, Masanori; Nishimura, Kenji; Obata, Fumiaki; Inagaki, Taizo; Minato, Masanori; Kishi, Fumi; Matsuura, Motokazu; Matsui, Naoko; Endo, Itsuro; Hann, Michael; Kishi, Seiji; Murakami, Taichi; Abe, Hideharu; Doi, Toshio
• Author Heading: Yoshimoto, Sakiya; Nagai, Kojiro; Shibata, Eriko; Ueda, Sayo; Ono, Hiroyuki; Tamaki, Masanori; Nishimura, Kenji; Obata, Fumiaki; Inagaki, Taizo; Minato, Masanori; Kishi, Fumi; Matsuura, Motokazu; Matsui, Naoko; Endo, Itsuro; Hann, Michael; Kishi, Seiji; Murakami, Taichi; Abe, Hideharu; Doi, Toshio
• Publication, Distribution, etc.: Faculty of Medicine Tokushima University
• Publication Date: 2017-02
• Publication Date (W3CDTF): 2017-02
• Alternative Title: 入院慢性腎臓病患者における血清アルブミン濃度に影響を与える因子; Serum albumin, proteinuria in hospitalized CKD patients
• Periodical title: The Journal of Medical Investigation
• No. or year of volume/issue: 64 1-2
• Volume: 64
• Issue: 1-2
• Pages: 146-152
• ISSN (Periodical Title): ISSN : 1349-6867; ISSN : 1343-1420
• Degree grantor/type: 徳島大学
• Date Granted: 2017-03-23
• Dissertation Number: 甲第3029号
• Degree Type: 博士（医学）
• Text Language Code: eng
• Subject Heading: Serum albumin concentration; Proteinuria; Chronic kidney disease; Postural change; Hospitalization
• Target Audience: 一般
• Note (General): Background : Serum albumin concentration (SAC) is a prognostic factor that is affected by many factors such as postural change, liver function and food intake. Chronic kidney disease (CKD) patients excrete proteinuria, have low-protein diet, and receive glucocorticoid therapy. No one has evaluated the most influential factors on SAC in CKD patients. Methods : A retrospective study. Hospitalized CKD patients with less than 1 g/ gCreatinine proteinuria receiving glucocorticoid therapy (n=28), with 1 or more g/gCreatinine proteinuria not receiving glucocorticoid therapy (n=36), and with 1 or more g/gCreatinine proteinuria receiving glucocorticoid therapy (n=39) were enrolled. SAC, hemoglobin, proteinuria and blood pressure at the last outpatient check-up before hospitalization, on the second day of hospitalization, at the last laboratory examination before discharge, as well as at the first outpatient follow-up after discharge were analyzed. Results : SAC decreased on the second day of hospitalization and increased at the first outpatient follow-up significantly in all groups. Unexpectedly, the change of SAC was irrelevant to the amount of proteinuria. Conclusions : SAC was affected by not only proteinuria, but also postural change, physical activity, and food in CKD patients. SAC should be analyzed by standardizing a patient’s condition during phlebotomy.
• Access Restrictions: インターネット公開
• Related Material (DOI): 10.2152/jmi.64.146
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 徳島大学 : 徳島大学機関リポジトリ

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