Intra-arterial high signals on arterial spin labeling perfusion images predict the occluded internal carotid artery segment

• Material Type: 博士論文
• Title: Intra-arterial high signals on arterial spin labeling perfusion images predict the occluded internal carotid artery segment
• Author/Editor: Sogabe, Shu; Satomi, Junichiro; Tada, Yoshiteru; Kanematsu, Yasuhisa; Kuwayama, Kazuyuki; Yagi, Kenji; Yoshioka, Shotaro; Mizobuchi, Yoshifumi; Mure, Hideo; Yamaguchi, Izumi; Abe, Takashi; Yamamoto, Nobuaki; Kitazato, Keiko T.; Kaji, Ryuji; Harada, Masafumi; Nagahiro, Shinji
• Author Heading: Sogabe, Shu; Satomi, Junichiro; Tada, Yoshiteru; Kanematsu, Yasuhisa; Kuwayama, Kazuyuki; Yagi, Kenji; Yoshioka, Shotaro; Mizobuchi, Yoshifumi; Mure, Hideo; Yamaguchi, Izumi; Abe, Takashi; Yamamoto, Nobuaki; Kitazato, Keiko T.; Kaji, Ryuji; Harada, Masafumi; Nagahiro, Shinji
• Publication, Distribution, etc.: Springer Berlin Heidelberg
• Publication Date: 2017-04-10
• Publication Date (W3CDTF): 2017-04-10
• Alternative Title: Arterial spin labeling灌流画像で得られる血管内高信号は内頚動脈の閉塞部位を予測する
• Periodical title: Neuroradiology
• No. or year of volume/issue: 59 6
• Volume: 59
• Issue: 6
• Pages: 587-595
• ISSN (Periodical Title): ISSN : 0028-3940; ISSN : 1432-1920
• Degree grantor/type: 徳島大学
• Date Granted: 2018-03-23
• Dissertation Number: 甲第3134号
• Degree Type: 博士（医学）
• Text Language Code: eng
• Subject Heading: Magnetic resonance imaging; Arterial spin labeling; Internal carotid artery occlusion; Occluded segment
• Target Audience: 一般
• Note (General): Introduction Arterial spin labeling (ASL) involves perfusion imaging using the inverted magnetization of arterial water. If the arterial arrival times are longer than the post-labeling delay, labeled spins are visible on ASL images as bright, high intra-arterial signals (IASs); such signals were found within occluded vessels of patients with acute ischemic stroke. The identification of the occluded segment in the internal carotid artery (ICA) is crucial for endovascular treatment. We tested our hypothesis that high IASs on ASL images can predict the occluded segment. Methods Our study included 13 patients with acute ICA occlusion who had undergone angiographic and ASL studies within 48 h of onset. We retrospectively identified the high IAS on ASL images and angiograms and recorded the occluded segment and the number of high IAS-positive slices on ASL images. The ICA segments were classified as cervical (C1), petrous (C2), cavernous (C3), and supraclinoid (C4). Results Of seven patients with intracranial ICA occlusion, five demonstrated high IASs at C1–C2, suggesting that high IASs could identify stagnant flow proximal to the occluded segment. Among six patients with extracranial ICA occlusion, five presented with high IASs at C3–C4, suggesting that signals could identify the collateral flow via the ophthalmic artery. None had high IASs at C1–C2. The mean number of high IAS-positive slices was significantly higher in patients with intra- than extracranial ICA occlusion. Conclusion High IASs on ASL images can identify slow stagnant and collateral flow through the ophthalmic artery in patients with acute ICA occlusion and help to predict the occlusion site.
• Format (IMT): application/pdf
• Access Restrictions: インターネット公開
• Related Material (DOI): 10.1007/s00234-017-1828-9
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 徳島大学 : 徳島大学機関リポジトリ

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