Updated Left Ventricular Diastolic Function Recommendations and Cardiovascular Events in Patients with Heart Failure Hospitalization

• Material Type: 博士論文
• Title: Updated Left Ventricular Diastolic Function Recommendations and Cardiovascular Events in Patients with Heart Failure Hospitalization
• Author/Editor: Torii, Yuta; Kusunose, Kenya; Yamada, Hirotsugu; Nishio, Susumu; Hirata, Yukina; Amano, Rie; Yamao, Masami; Zheng, Robert; Saijo, Yoshihito; Yamada, Nao; Ise, Takayuki; Yamaguchi, Koji; Yagi, Shusuke; Soeki, Takeshi; Wakatsuki, Tetsuzo; Sata, Masataka
• Author Heading: Torii, Yuta; Kusunose, Kenya; Yamada, Hirotsugu; Nishio, Susumu; Hirata, Yukina; Amano, Rie; Yamao, Masami; Zheng, Robert; Saijo, Yoshihito; Yamada, Nao; Ise, Takayuki; Yamaguchi, Koji; Yagi, Shusuke; Soeki, Takeshi; Wakatsuki, Tetsuzo; Sata, Masataka
• Publication, Distribution, etc.: The American Society of Echocardiography|Elsevier
• Publication Date: 2019-08-01
• Publication Date (W3CDTF): 2019-08-01
• Alternative Title: 更新された左室拡張機能評価勧告と心不全入院患者における心血管イベント
• Periodical title: Journal of the American Society of Echocardiography
• No. or year of volume/issue: 32 10
• Volume: 32
• Issue: 10
• Pages: 1286-1297.e2
• ISSN (Periodical Title): ISSN : 0894-7317
• Degree grantor/type: 徳島大学
• Date Granted: 2020-03-23
• Dissertation Number: 甲第3355号
• Degree Type: 博士（医学）
• Text Language Code: eng
• Subject Heading: Diastolic dysfunction; Echocardiography; Left atrial pressure; Readmission risk; Cardiovascular event
• Target Audience: 一般
• Note (General): Background: Evaluation of diastolic dysfunction is crucial in determining elevated left atrial pressure. However, a validation of the long-term prognostic value of the newly proposed algorithm updated in 2016 has not been performed. The aim of the present study was to investigate the relative value of the updated 2016 diastolic dysfunction grading system for the incidence of readmission in patients with heart failure (HF) with reduced ejection fraction (HFrEF) and HF with preserved ejection fraction (HFpEF). Methods: Two hundred thirty-two patients hospitalized with HF were retrospectively evaluated. Subjects were divided into two subgroups: those with HFrEF (n = 127) and those with HFpEF (n = 105). Readmission risk scores were calculated using the Yale Center for Outcomes Research and Evaluation HF, LACE index, and HOSPITAL scores. The primary end point was readmission following HF and cardiac death. Results: Over a period of 24 months, 86 patients were either readmitted or died. Multivariate Cox analysis was performed on both the HFrEF and HFpEF groups. In the HFrEF group, both the 2009 and 2016 algorithms had superior incremental value for the association of the primary end point to several readmission risk scores. In the HFpEF group, only the 2016 algorithm led to significant improvement in association with the primary end point. The 2016 algorithm had incremental value over several readmission risk scores alone. Conclusions: The recommendations of the 2016 algorithm can be useful for readmission and cardiac mortality risk assessment in patients with HFrEF and HFpEF. The use of echocardiography to estimate elevated left atrial pressure appears to identify a higher risk group and may allow a more tailored approach to therapy.
• Format (IMT): application/pdf
• Access Restrictions: インターネット公開
• Related Material (DOI): 10.1016/j.echo.2019.06.006
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 徳島大学 : 徳島大学機関リポジトリ

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