Effect of Biopsy Technique on the Survival Rate of Malignant Melanoma Patients

• Material Type: 博士論文
• Title: Effect of Biopsy Technique on the Survival Rate of Malignant Melanoma Patients
• Author/Editor: Yamashita, Yutaro; Hashimoto, Ichiro; Abe, Yoshiro; Seike, Takuya; Okawa, Katsumasa; Senzaki, Yuichi; Murao, Kazutoshi; Kubo, Yoshiaki; Nakanishi, Hideki
• Author Heading: Yamashita, Yutaro; Hashimoto, Ichiro; Abe, Yoshiro; Seike, Takuya; Okawa, Katsumasa; Senzaki, Yuichi; Murao, Kazutoshi; Kubo, Yoshiaki; Nakanishi, Hideki
• Publication, Distribution, etc.: Korean Society of Plastic and Reconstructive Surgeons
• Publication Date: 2014-03-12
• Publication Date (W3CDTF): 2014-03-12
• Alternative Title: 皮膚悪性黒色腫患者の生存率に生検方法が及ぼす影響; Effect of biopsy on survival of melanoma patients
• Periodical title: Archives of Plastic Surgery
• No. or year of volume/issue: 41 2
• Volume: 41
• Issue: 2
• Pages: 122-125
• ISSN (Periodical Title): ISSN : 2234-6163; ISSN : 2234-6171
• Degree grantor/type: 徳島大学
• Date Granted: 2019-12-26
• Dissertation Number: 乙第2110号
• Degree Type: 博士（医学）
• Text Language Code: eng
• Subject Heading: Melanoma; Prognosis; Survival rate
• Target Audience: 一般
• Note (General): Background Cutaneous malignant melanoma has a poor prognosis. The detrimental effect of incisional biopsies on the outcome of malignant melanoma has been debated. The aim of this study was to determine the effect of the presence and type of biopsy on the prognosis of malignant melanoma. Methods The medical records of 109 malignant melanoma patients treated at Tokushima University Hospital from 1983 to 2007 were reviewed. After excluding 28 cases with stage 0 disease or incomplete data, 81 cases were analyzed in detail with respect to patient sex, age, tumor site, clinical stage at diagnosis, presence of ulceration or lymph node metastasis, and prognosis. The five-year survival and five-year disease-free survival rates of patients who underwent incisional or excisional biopsies were compared with those who did not undergo a biopsy. Results The male-to-female ratio was 1:1.19. The mean age was 61.3 years (range, 19–93 years). The most common site was a lower extremity, and the most common clinical stage was stage II. No significant differences in clinicopathological features, five-year survival rates, and five-year disease-free survival rates were observed among the three groups. Conclusions The presence and type of biopsy neither affected the metastatic rate nor the prognosis of malignant melanoma. The use of incisional biopsies is not encouraged because tumor thickness cannot be measured accurately. However, they may be helpful for confirming the diagnosis if an excisional biopsy cannot be performed.
• Format (IMT): application/pdf
• Access Restrictions: インターネット公開
• Rights (production): This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( http://creativecommons.org/licenses/by-nc/3.0/ ), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
• Related Material (DOI): 10.5999/aps.2014.41.2.122
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 徳島大学 : 徳島大学機関リポジトリ

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