Inactivation of Extended-spectrum β-lactamase (ESBL)-producing Escherichia coli by UVA-LED irradiation system

• Material Type: 博士論文
• Title: Inactivation of Extended-spectrum β-lactamase (ESBL)-producing Escherichia coli by UVA-LED irradiation system
• Author/Editor: Ulfa, Maria; Azuma, Momoyo; Sato, Masami; Shimohata, Takaaki; Fukushima, Shiho; Kido, Junko; Nakamoto, Mariko; Uebanso, Takashi; Mawatari, Kazuaki; Emoto, Takahiro; Akutagawa, Masatake; Kinouchi, Yohsuke; Takahashi, Akira
• Author Heading: Ulfa, Maria; Azuma, Momoyo; Sato, Masami; Shimohata, Takaaki; Fukushima, Shiho; Kido, Junko; Nakamoto, Mariko; Uebanso, Takashi; Mawatari, Kazuaki; Emoto, Takahiro; Akutagawa, Masatake; Kinouchi, Yohsuke; Takahashi, Akira
• Publication, Distribution, etc.: Tokushima University Faculty of Medicine
• Publication Date: 2020-02
• Publication Date (W3CDTF): 2020-02
• Alternative Title: UVA-LED照射装置を用いた、基質特異性拡張型βラクタマーゼ産生大腸菌の殺菌; Inactivation of ESBL-E. coli
• Periodical title: The Journal of Medical Investigation
• No. or year of volume/issue: 67 1-2
• Volume: 67
• Issue: 1-2
• Pages: 163-169
• ISSN (Periodical Title): ISSN : 1349-6867; ISSN : 1343-1420
• Degree grantor/type: 徳島大学
• Date Granted: 2020-03-23
• Dissertation Number: 甲第3410号
• Degree Type: 博士（栄養学）
• Text Language Code: eng
• Subject Heading: extended-spectrum β-lactamase (ESBL); ESBL-E. coli; E. coli; UVA-LED irradiation
• Target Audience: 一般
• Note (General): The prevalence of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli is increasing rapidly and spreading worldwide, particularly in Asia, compared to other regions. In the last ten years, in our hospital, in particular, there has been a < 30% increase. To prevent the spread of ESBL in hospitals and the community, the ultraviolet (UV) A-light-emitting diode (LED) irradiation device was used to inactivate ESBL-E. coli in human livestock and the environment. ESBL-E. coli and E. coli bacterial samples were collected from patients at Tokushima University Hospital (Tokushima City, Japan). The UVA-LED irradiation system had 365 nm single wavelength, and the current of the circuit was set to 0.23 or 0.50 A consistently. Results demonstrated that UVA-LED was useful for the inactivation of ESBL-E. coli and E. coli. The minimum energy dosage required to inactivate ESBL-E. coli and E. coli was 40.76 J/cm2 (45 min) in the first type of UVA-LED and 38.85 J/cm2 (5 min) in the second type. There were no significant differences between ESBL-E. coli and E. coli. The inactivation of ESBL-E. coli was dependent on energy. These findings suggest that UVA-LED with 365 nm single wavelength could be useful for surface decontamination in healthcare facilities.
• Format (IMT): application/pdf
• Access Restrictions: インターネット公開
• Related Material (DOI): 10.2152/jmi.67.163
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 徳島大学 : 徳島大学機関リポジトリ

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http://repo.lib.tokushima-u.ac.jp/files/public/11/114642/20200420170747783986/k3410_abstract_review.pdf fulltext

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