The influences of psychological stress in early life on sexual maturation and sexual behavior in male and female rats

• Material Type: 博士論文
• Title: The influences of psychological stress in early life on sexual maturation and sexual behavior in male and female rats
• Author/Editor: Yano, Kiyohito; Matsuzaki, Toshiya; Iwasa, Takeshi; Mayila, Yiliyasi; Yanagihara, Rie; Tungalagsuvd, Altankhuu; Munkhzaya, Munkhsaihan; Tokui, Takako; Kamada, Shuhei; Hayashi, Aki; Masaki, Rie; Aoki, Hidenori; Tamura, Kou; Irahara, Minoru
• Author Heading: Yano, Kiyohito; Matsuzaki, Toshiya; Iwasa, Takeshi; Mayila, Yiliyasi; Yanagihara, Rie; Tungalagsuvd, Altankhuu; Munkhzaya, Munkhsaihan; Tokui, Takako; Kamada, Shuhei; Hayashi, Aki; Masaki, Rie; Aoki, Hidenori; Tamura, Kou; Irahara, Minoru
• Publication, Distribution, etc.: Wiley|Japan Society for Reproductive Medicine
• Publication Date: 2019-12-26
• Publication Date (W3CDTF): 2019-12-26
• Alternative Title: 生後早期の心理的ストレスが雌雄ラットの性成熟、性行動に与える影響
• Periodical title: Reproductive Medicine and Biology
• No. or year of volume/issue: 19 2
• Volume: 19
• Issue: 2
• Pages: 135-141
• ISSN (Periodical Title): ISSN : 1447-0578
• Degree grantor/type: 徳島大学
• Date Granted: 2020-03-23
• Dissertation Number: 甲第3364号
• Degree Type: 博士（医学）
• Text Language Code: eng
• Subject Heading: maternal separation; sexual maturation; sexual behavior; early life stress; psychological stress; neonatal period
• Target Audience: 一般
• Note (General): Purpose: We studied the influence of psychological stress during the early neonatal period on sexual maturation and sexual behavior in rats. Methods: Neonatal male and female rats were divided into control (C) and maternal separation (MS) groups (n = 20‐24 per group). The pups in the MS groups were placed in isolation cages for 240 minutes/d from postnatal days 2‐11. Vaginal opening (VO) in females and preputial separation (PS) in males (indicators of sexual maturation) were monitored, as was the estrous cycle in females. Thereafter, sexual behavior was monitored twice at 13 and 15 weeks of age. Results: As for sexual maturation, the onset of PS occurred significantly earlier in the MS group than in the C group, whereas the onset of VO did not differ between the groups. The length of the estrous cycle did not differ between the groups. The frequencies of sexual behaviors did not differ between the groups in either sex. Conclusions: In conclusion, early‐life psychological stress induced by MS advanced sexual maturation in male rats, whereas it did not affect sexual maturation in female rats. On the other hand, early‐life psychological stress might not affect sexual behavior in adulthood in either sex.
• Format (IMT): application/pdf
• Access Restrictions: インターネット公開
• Rights (production): This is an open access article under the terms of the Creative Commons Attribution License ( https://creativecommons.org/licenses/by/4.0/ ), which permits use, distribution and reproduction in any medium, provided the original work is properly cited. © 2019 The Authors. Reproductive Medicine and Biology published by John Wiley & Sons Australia, Ltd on behalf of Japan Society for Reproductive Medicine.
• Related Material (DOI): 10.1002/rmb2.12313
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 徳島大学 : 徳島大学機関リポジトリ

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