A new combined index of SUVmax of lymph node in PET/CT by a weighting coefficient plus its maximum minor axis in CECT to evaluate occult lymph node metastasis in clinical N0 patients with tongue cancer

• Material Type: 博士論文
• Title: A new combined index of SUVmax of lymph node in PET/CT by a weighting coefficient plus its maximum minor axis in CECT to evaluate occult lymph node metastasis in clinical N0 patients with tongue cancer
• Author/Editor: Kanamura, Ryo; Suzuki, Motoyuki; Otozai, Shinji; Yoshii, Tadashi; Okamoto, Hidehiko; Kitamura, Yoshiaki; Abe, Koji; Fujii, Takashi; Takeda, Noriaki
• Author Heading: Kanamura, Ryo; Suzuki, Motoyuki; Otozai, Shinji; Yoshii, Tadashi; Okamoto, Hidehiko; Kitamura, Yoshiaki; Abe, Koji; Fujii, Takashi; Takeda, Noriaki
• Publication, Distribution, etc.: Tokushima University Faculty of Medicine
• Publication Date: 2021-02
• Publication Date (W3CDTF): 2021-02
• Alternative Title: リンパ節のPET/CTによるSUVmaxに重み付け係数を乗じてCECTの最大短径を加えた新しいcombined indexによる舌癌の臨床的N0症例の潜在的リンパ節転移の評価; Combined index to evaluate N0 neck
• Periodical title: The Journal of Medical Investigation
• No. or year of volume/issue: 68 1-2
• Volume: 68
• Issue: 1-2
• Pages: 154-158
• ISSN (Periodical Title): ISSN : 1349-6867; ISSN : 1343-1420
• Degree grantor/type: 徳島大学
• Date Granted: 2021-03-17
• Dissertation Number: 甲第3487号
• Degree Type: 博士（医学）
• Text Language Code: eng
• Subject Heading: Tongue cancer; lymph node metastasis; clinical N0 neck; occult nodal metastasis; PET/CT
• Target Audience: 一般
• Note (General): To predict occult nodal metastasis in clinical N0 patients with tongue cancer, we developed combined index (CI) : SUVmax of the largest lymph node in PET/CT by weighting coefficient plus its maximum minor axis (< 10 mm) in contrast-enhanced CT (CECT). In this retrospective study, 57 clinical N0 patients with tongue cancer, who underwent elective supraomohyoid neck dissection at cervical levels of I-III were enrolled. The cutoff value of SUVmax of 2.0 obtained using receiver operating characteristic (ROC) analysis predicted the postoperative positive cervical levels containing metastatic lymph nodes from clinical N0 cervical levels in tongue cancer patients with a sensitivity of 54.5% and a specificity of 78.2%. The cutoff value of CI with weighting coefficient of 1.5 obtained using ROC analysis was 9.8 at the maximum area under the curve of 0.750. The cutoff value of 9.8 predicted the postoperative positive cervical levels containing metastatic lymph nodes from clinical N0 cervical levels in tongue cancer patients with a sensitivity of 68.2% and a specificity of 81.5%. These findings suggest that CI of functional PET/CT and morphological CECT components might improve the diagnostic performance of occult nodal metastasis to select clinical N0 patients with tongue cancer preferable for elective neck dissection.
• Format (IMT): application/pdf
• Access Restrictions: インターネット公開
• Related Material (DOI): 10.2152/jmi.68.154
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 徳島大学 : 徳島大学機関リポジトリ

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http://repo.lib.tokushima-u.ac.jp/files/public/11/115970/20210519102352978025/k3487_abstract_review.pdf fulltext

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