Clinical characteristics of hyponatremia in patients receiving nutrition support : A cross-sectional study evaluated by bioelectrical impedance analysis

• Material Type: 博士論文
• Title: Clinical characteristics of hyponatremia in patients receiving nutrition support : A cross-sectional study evaluated by bioelectrical impedance analysis
• Author/Editor: Yano, Mayumi; Inoue, Arisa; Toda, Akiyo; Takahashi, Michiko; Usami, Makoto; Hamada, Yasuhiro
• Author Heading: Yano, Mayumi; Inoue, Arisa; Toda, Akiyo; Takahashi, Michiko; Usami, Makoto; Hamada, Yasuhiro
• Publication, Distribution, etc.: Tokushima University Faculty of Medicine
• Publication Date: 2021-02
• Publication Date (W3CDTF): 2021-02
• Alternative Title: 栄養サポート介入患者における低ナトリウム血症の要因 : 生体電気インピーダンス法による横断研究; Clinical Characteristics of Hyponatremia
• Periodical title: The Journal of Medical Investigation
• No. or year of volume/issue: 68 1-2
• Volume: 68
• Issue: 1-2
• Pages: 112-118
• ISSN (Periodical Title): ISSN : 1349-6867; ISSN : 1343-1420
• Degree grantor/type: 徳島大学
• Date Granted: 2021-03-23
• Dissertation Number: 甲第3511号
• Degree Type: 博士（栄養学）
• Text Language Code: eng
• Subject Heading: Hyponatremia; bioelectrical impedance analysis; fluid volume imbalance; the ratio of extracellular water to total body water
• Target Audience: 一般
• Note (General): Background & aims : We investigated the contributing factors of hyponatremia in patients on nutrition support using bioelectrical impedance analysis (BIA). Methods : Thirty patients administered enteral or parenteral nutrition support for at least 72 hours were studied. We collected nutritional and electrolyte intake, serum biochemical parameters, and body composition measured by BIA. Patients were classified into two groups according to their serum sodium levels : (1) Normanatremia group, 135–145 mEq / L (n = 18) and (2) Hyponatremia group, less than 135 mEq / L (n = 12), and their characteristics were analyzed. Results : There were no significant differences between the Normonatremia and Hyponatremia groups in terms of energy, protein, and sodium intake. Serum biochemical parameters other than serum sodium and chloride levels were comparable between the two groups. On the other hand, the ratio of extracellular water to total body water (ECW / TBW) obtained by BIA was significantly higher in the Hyponatremia group than in the Normonatremia group. Further, an elevated ECW / TBW significantly and negatively correlated with serum albumin level. Conclusions : Regardless of sodium intake, higher ECW / TBW was associated with hyponatremia in patients on nutrition support. ECW / TBW may be an important clinical parameter relevant to the nutritional care of hyponatremia.
• Format (IMT): application/pdf
• Access Restrictions: インターネット公開
• Related Material (DOI): 10.2152/jmi.68.112
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 徳島大学 : 徳島大学機関リポジトリ

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