Prefrontal cortex activity induced by periodontal afferent inputs downregulates occlusal force

• Material Type: 博士論文
• Title: Prefrontal cortex activity induced by periodontal afferent inputs downregulates occlusal force
• Author/Editor: Kishimoto, Takahiro; Goto, Takaharu; Ichikawa, Tetsuo
• Author Heading: Kishimoto, Takahiro; Goto, Takaharu; Ichikawa, Tetsuo
• Publication, Distribution, etc.: Springer Nature
• Publication Date: 2019-08-22
• Publication Date (W3CDTF): 2019-08-22
• Alternative Title: 求心性の歯周組織感覚入力により誘発された前頭前野の活動は咬合力を抑制する
• Periodical title: Experimental Brain Research
• No. or year of volume/issue: 237 11
• Volume: 237
• Issue: 11
• Pages: 2767-2774
• ISSN (Periodical Title): ISSN : 0014-4819; ISSN : 1432-1106
• Degree grantor/type: 徳島大学
• Date Granted: 2021-03-23
• Dissertation Number: 甲第3491号
• Degree Type: 博士（歯学）
• Text Language Code: eng
• Subject Heading: Prefrontal cortex; Periodontal afferent inputs; Functional near-infrared spectroscopy; Occlusal force
• Target Audience: 一般
• Note (General): The prefrontal cortex (PFC) plays an important role in several cognitive functions, such as planning, decision making, and social behavior. We previously reported that periodontal sensory input significantly increases PFC activity during the motor task of maintaining occlusal (biting) force. However, the relationships between periodontal sensation, PFC activity, and the performance of motor tasks, have not been evaluated in detail. Therefore, using functional near-infrared spectroscopy, we investigated PFC activity by monitoring changes in cerebral blood flow (CBF) to specific areas of the PFC that corresponded to changes in occlusal force generated during 4 different biting tasks: 1) occlusion with the central incisor with an interocclusal distance of 5 mm (BI-5 mm); or 2) 10 mm (BI-10 mm); 3) occlusion with the first molars with an interocclusal distance of 5 mm (BM-5 mm), or 4) 10 mm (BM-10 mm). Occlusion of molars generated increased PFC regional CBF as the interocclusal distance decreased (BM-10 mm vs BM-5 mm). No significant differences in CBF during occlusion of incisors were found when comparing 5 mm and 10 mm intercostal distances (BI-5 mm vs BI-10 mm). The mean occlusal force generated by BM-5 mm occlusion was significantly lower than that generated by BM-10 mm occlusion. Taken together, our results suggest that the PFC decreases efferent signaling to motor units, to reduce occlusal force generated when periodontal sensation, which is greater when the interocclusal distance is reduced, is primarily responsible for maintaining occlusal force in the absence of sensations from the temporomandibular joint and muscle spindles.
• Format (IMT): application/pdf
• Access Restrictions: インターネット公開
• Related Material (DOI): 10.1007/s00221-019-05630-y
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 徳島大学 : 徳島大学機関リポジトリ

Table of Contents

http://repo.lib.tokushima-u.ac.jp/files/public/11/116057/20210615110556646151/k3491_abstract.pdf fulltext

http://repo.lib.tokushima-u.ac.jp/files/public/11/116057/20210615110557263135/k3491_review.pdf fulltext

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