Diagnostic usefulness of denervation edema in the multifidus muscles using 3-Tesla magnetic resonance imaging in cervical radiculopathy

• Material Type: 博士論文
• Title: Diagnostic usefulness of denervation edema in the multifidus muscles using 3-Tesla magnetic resonance imaging in cervical radiculopathy
• Author/Editor: Yoshida, Takeshi; Suwazono, Shugo; Sueyoshi, Takeshi; Izumi, Yuishin; Nodera, Hiroyuki
• Author Heading: Yoshida, Takeshi; Suwazono, Shugo; Sueyoshi, Takeshi; Izumi, Yuishin; Nodera, Hiroyuki
• Publication, Distribution, etc.: Wiley|American Association of Neuromuscular & Electrodiagnostic Medicine
• Publication Date: 2020-12-13
• Publication Date (W3CDTF): 2020-12-13
• Alternative Title: 頚椎症性神経根症の診断における3テスラMRIによる傍脊柱筋の脱神経に伴う浮腫性信号異常検出の有用性の検討
• Periodical title: Muscle & Nerve
• No. or year of volume/issue: 63 3
• Volume: 63
• Issue: 3
• Pages: 365-370
• ISSN (Periodical Title): ISSN : 1097-4598
• Degree grantor/type: 徳島大学
• Date Granted: 2021-09-30
• Dissertation Number: 甲第3557号
• Degree Type: 博士（医学）
• Text Language Code: eng
• Subject Heading: Magnetic resonance imaging; cervical radiculopathy; multifidus muscle; denervation edema; denervated muscle; multifidus
• Target Audience: 一般
• Note (General): Introduction/Aims: Diagnosing cervical radiculopathy (CR) can be difficult because of symptomatic overlap with peripheral neuropathies. In this retrospective observational study, we aimed to determine whether short-tau inversion recovery (STIR) magnetic resonance imaging (MRI) sequences are useful for detecting signs of denervation in the multifidus muscles in patients with CR. Methods: We analyzed the data of 18 patients with CR who developed arm weakness within 1 year. We also included 10 patients with sensorimotor symptoms involving the upper extremities who did not have intervertebral foraminal stenosis on MRI as controls. For each patient with CR, the signal intensity (SI) of the affected multifidus muscles was measured and compared to that on the contralateral side (signal intensity ratio: SIR). Results: Control patients without CR did not exhibit STIR signal abnormalities in the multifidus muscles. Most of the 18 patients with CR were male (83.3%), and the mean age was 59.4 years. Thirteen of 18 CR patients (72.2%) were determined to have STIR signal abnormalities by a radiologist. The mean SIR in the 13 patients with increased SI was significantly higher than that in the five patients without signal abnormalities (1.23 vs. 0.97, p=0.004), supporting the radiologist’s diagnosis. The distribution of signal abnormalities closely followed those identified via clinical and electrophysiological tests, especially severe weakness (p=0.044). Discussion: Denervation edema of the multifidus muscles can be detected in CR and correlates with clinical/electrophysiological tests and weakness severity, which may aid in CR diagnostics.
• Format (IMT): application/pdf
• Access Restrictions: インターネット公開
• Rights (production): © 2020 Wiley Periodicals LLC This is the peer reviewed version of the following article: Yoshida, T, Suwazono, S, Sueyoshi, T, Izumi, Y, Nodera, H. Diagnostic usefulness of denervation edema in the multifidus muscles using 3-Tesla magnetic resonance imaging in cervical radiculopathy. Muscle & Nerve. 2021; 63: 365– 370, which has been published in final form at https://doi.org/10.1002/mus.27142. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wileyʼs version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.
• Related Material (DOI): 10.1002/mus.27142
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 徳島大学 : 徳島大学機関リポジトリ

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