γ‑tocotrienol prevents 5‑FU‑induced reactive oxygen species production in human oral keratinocytes through the stabilization of 5‑FU‑induced activation of Nrf2

• Material Type: 博士論文
• Title: γ‑tocotrienol prevents 5‑FU‑induced reactive oxygen species production in human oral keratinocytes through the stabilization of 5‑FU‑induced activation of Nrf2
• Author/Editor: 高野, 栄之; 桃田, 幸弘; 可児, 耕一; 青田, 桂子; 山村, 佳子; 山ノ井, 朋子; 東, 雅之
• Author Heading: 高野, 栄之; 桃田, 幸弘; 可児, 耕一; 青田, 桂子; 山村, 佳子; 山ノ井, 朋子 ヤマノイ, トモコ; 東, 雅之
• Publication, Distribution, etc.: Spandidos Publications
• Publication Date: 2015-01-26
• Publication Date (W3CDTF): 2015-01-26
• Alternative Title: γ‑トコトリエノールは5‑FUにより誘導されるNrf2を安定化させることにより5‑FUによる口腔粘膜上皮細胞の活性酸素産生を抑制する; PREVENTION OF ROS GENERATION VIA STABILIZATION OF Nrf2 ACTIVATION
• Periodical title: International Journal of Oncology
• No. or year of volume/issue: 46 4
• Volume: 46
• Issue: 4
• Pages: 1453-1460
• ISSN (Periodical Title): ISSN : 10196439; ISSN : 17912423
• Dissertation Number: 甲口第389号
• Text Language Code: und
• Subject Heading: oral keratinocytes; oral cancer; mucositis; reactive oxygen species; 5‑FU; γ‑tocotrienol; Nrf2
• Target Audience: 一般
• Format (IMT): application/pdf
• Source: fulltext; https://tokushima-u.repo.nii.ac.jp/record/2002603/files/LID201505071004.pdf
• Access Restrictions: インターネット公開
• Rights (production): Copyright: © Takano et al. This is an open access article distributed under the terms of a Creative Commons Attribution License [CC BY_NC 3.0].
• Periodical Title (NCID): AA10992511; https://ci.nii.ac.jp/ncid/AA10992511
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 徳島大学 : 徳島大学機関リポジトリ

• Summary, etc.: Chemotherapy‑induced oral mucositis is a common adverse event in patients with oral squamous cell carcinoma, and is initiated through a variety of mec...