博士論文

Down-regulation of MDR1 by Ad-DKK3 via Akt/NFκB pathways augments the anti-tumor effect of temozolomide in glioblastoma cells and a murine xenograft model

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Down-regulation of MDR1 by Ad-DKK3 via Akt/NFκB pathways augments the anti-tumor effect of temozolomide in glioblastoma cells and a murine xenograft model

Material type
博士論文
Author
藤原, 敏孝ほか
Publisher
Springer Science+Business Media, LLC
Publication date
2018-05-19
Material Format
Digital
Capacity, size, etc.
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Name of awarding university/degree
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Summary, etc.:

Background: Glioblastoma multiforme (GBM) is the most malignant of brain tumors. Acquired drug resistance is a major obstacle for successful treatment...

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  • Tokushima University Institutional Repository

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Digital

Material Type
博士論文
Author/Editor
藤原, 敏孝
溝渕, 佳史
中島, 公平
影治, 照喜
松﨑, 和仁
キタザト, ケイコ
オオツカ, リョウタロウ
原, 慶次郎
牟礼, 英生
岡﨑, 敏之
桑山, 一行
永廣, 信治
髙木, 康志
Publication, Distribution, etc.
Publication Date
2018-05-19
Publication Date (W3CDTF)
2018-05-19
Alternative Title
膠芽腫細胞およびマウス背部皮下モデルにおいて,アデノウイルスベクターを用いたDKK3の導入はAkt/NFκB経路を介してMDR1の発現を抑制し,テモゾロミドによる抗腫瘍効果を増強する
Periodical title
Journal of Neuro-Oncology
No. or year of volume/issue
139 2