MuRF1 deficiency prevents age-related fat weight gain, possibly through accumulation of PDK4 in skeletal muscle mitochondria in older mice

• Material Type: 博士論文
• Title: MuRF1 deficiency prevents age-related fat weight gain, possibly through accumulation of PDK4 in skeletal muscle mitochondria in older mice
• Author/Editor: 杉浦, 宏祐; 平坂, 勝也; マエダ, タスク; 内田, 貴之; 岸本, 幸治; オオアラダ, モトコ; Labeit, Siegfried; Ulla, Anayt; 榊原, 伊織; 中尾, 玲子; 西良, 浩一; 二川, 健
• Author Heading: 杉浦, 宏祐; 平坂, 勝也; マエダ, タスク マエダ, タスク; 内田, 貴之; 岸本, 幸治; オオアラダ, モトコ オオアラダ, モトコ; Labeit, Siegfried; Ulla, Anayt; 榊原, 伊織; 中尾, 玲子; 西良, 浩一; 二川, 健
• Publication, Distribution, etc.: Wiley
• Publication Date: 2021-06-29
• Publication Date (W3CDTF): 2021-06-29
• Alternative Title: 老齢マウスにおいてMuRF1欠乏は筋ミトコンドリア内のPDK4蓄積を介して加齢による脂肪増加を抑制する; MuRF1 regulates lipid metabolism
• Periodical title: Journal of Orthopaedic Research
• No. or year of volume/issue: 40 5
• Volume: 40
• Issue: 5
• Pages: 1026-1038
• ISSN (Periodical Title): ISSN : 1554527X
• Dissertation Number: 甲医第1514号
• Text Language Code: und
• Subject Heading: Muscle atrophy; Muscle RING finger 1 (MuRF1); lipid metabolism; Pyruvate dehydrogenase kinase 4 (PDK4); SUMO modification
• Target Audience: 一般
• Format (IMT): application/pdf
• Source: fulltext; https://tokushima-u.repo.nii.ac.jp/record/2009483/files/k3562_fulltext.pdf
• Access Restrictions: インターネット公開
• Rights (production): © 2021 Orthopaedic Research Society. Published by Wiley Periodicals LLC
• Periodical Title (NCID): AA10625350; https://ci.nii.ac.jp/ncid/AA10625350
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 徳島大学 : 徳島大学機関リポジトリ

• Summary, etc.: Recent studies show that muscle mass and metabolic function are interlinked. Muscle RING finger 1 (MuRF1) is a critical muscle-specific ubiquitin liga...