A polo-like kinase inhibitor identified by computational repositioning attenuates pulmonary fibrosis

• Material Type: 博士論文
• Title: A polo-like kinase inhibitor identified by computational repositioning attenuates pulmonary fibrosis
• Author/Editor: 今倉, 健; 佐藤, 正大; 小山, 壱也; 小川, 博久; 新村, 貴博; ムラカミ, コウジン; 山下, 雄也; 土師, 恵子; 内藤, 伸仁; 香川, 耕造; 河野, 弘; 座間味, 義人; 石澤, 啓介; 西岡, 安彦
• Author Heading: 今倉, 健 イマクラ, タケシ; 佐藤, 正大 サトウ, セイダイ; https://nrid.nii.ac.jp/ja/search/?qm=80530899; 小山, 壱也; 小川, 博久 オガワ, ヒロヒサ; 新村, 貴博; ムラカミ, コウジン ムラカミ, コウジン; 山下, 雄也 ヤマシタ, ユウヤ; 土師, 恵子; 内藤, 伸仁 ナイトウ, ノブヒト; 香川, 耕造 カガワ, コウゾウ; 河野, 弘 カワノ, ヒロシ; 座間味, 義人 ザマミ, ヨシト; https://nrid.nii.ac.jp/ja/search/?qm=70550250; 石澤, 啓介 イシザワ, ケイスケ; https://nrid.nii.ac.jp/ja/search/?qm=60398013; 西岡, 安彦 ニシオカ, ヤスヒコ
• Publication, Distribution, etc.: Springer Nature
• Publication Date: 2023-06-02
• Publication Date (W3CDTF): 2023-06-02
• Alternative Title: コンピュータ上でのドラッグ・リポジショニングにより同定したPLK阻害薬は肺線維化を抑制する
• Periodical title: Respiratory Research
• No. or year of volume/issue: 24
• Volume: 24
• Pages: 148-
• ISSN (Periodical Title): ISSN : 1465993X
• Dissertation Number: 甲医第1594号
• Text Language Code: und
• Subject Heading: Polo-like kinase; Pulmonary fibrosis; In silico screening; Myofibroblast; Lung epithelial cell
• Target Audience: 一般
• Format (IMT): application/pdf
• Source: fulltext; https://tokushima-u.repo.nii.ac.jp/record/2011774/files/k3769_fulltext.pdf
• Access Restrictions: インターネット公開
• Rights (production): This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
• Related Material (DOI): 10.1186/s12931-023-02446-x
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 徳島大学 : 徳島大学機関リポジトリ

• Summary, etc.: Background: Idiopathic pulmonary fibrosis (IPF) is a fatal fibrotic lung disease with few effective therapeutic options. Recently, drug repositioning,...