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Exercise enhances skeletal muscle regeneration by promoting senescence in fibro-adipogenic progenitors

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Exercise enhances skeletal muscle regeneration by promoting senescence in fibro-adipogenic progenitors

Material type
文書・図像類
Author
Saito, Yほか
Publisher
札幌医科大学医学部
Publication date
2021-03-31
Material Format
Digital
Capacity, size, etc.
-
NDC
-
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Detailed bibliographic record

Summary, etc.:

運動刺激に応答して生じる骨格筋間葉系前駆細胞(Fibro-adipogenic Progenitors: FAPs)の細胞老化が,骨格筋の再生に重要であることを明らかにした.一方で,慢性炎症性筋疾患モデルマウスではFAP の細胞老化が不十分で,運動がむしろ筋の線維化を悪化させることがわかった.さらに...

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Bibliographic Record

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Digital

Material Type
文書・図像類
Author/Editor
Saito, Y
Chikenji, TS
Matsumura, T
Nakano, M
Fujimiya, M
Publication, Distribution, etc.
Publication Date
2021-03-31
Publication Date (W3CDTF)
2021-03-31
Periodical title
札幌医学雑誌 = The Sapporo Medical Journal
No. or year of volume/issue
89 1-6
Volume
89