Prolonged oxidative stress and delayed tissue repair exacerbate acetaminophen-induced liver injury in aged mice

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Summary, etc.：: マウスにアセトアミノフェンを投与して急性劇症肝炎を誘導すると，中心静脈域にネクローシスによる大量の肝細胞死が誘導される．障害後は，速やかに障害が解消され，障害後48 時間後には活発な肝細胞増殖が誘導され，組織再生が進行する．老齢マウスでは，アセトアミノフェン代謝産物の処理能力低下による障害の持続，障...

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Material Type: 文書・図像類
Title: Prolonged oxidative stress and delayed tissue repair exacerbate acetaminophen-induced liver injury in aged mice
Author/Editor: TANIMIZU, Naoki
ICHINOHE, Norihisa
SUZUKI, Hiromu
MITAKA, Toshihiro
Author Heading: TANIMIZU, Naoki
ICHINOHE, Norihisa
SUZUKI, Hiromu
MITAKA, Toshihiro
Publication, Distribution, etc.: 札幌医科大学医学部
Publication Date: 2021-03-31
Publication Date (W3CDTF): 2021-03-31
Periodical title: 札幌医学雑誌 = The Sapporo Medical Journal
No. or year of volume/issue: 89 1-6
Volume: 89
Issue: 1-6
Pages: 48-49
ISSN (Periodical Title): ISSN : 0036-472X
Text Language Code: jpn
Target Audience: 一般
Access Restrictions: 限定公開
Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）
https://irdb.nii.ac.jp
Original Data Provider (Database): 札幌医科大学 : 札幌医科大学学術機関リポジトリ