Effect of IL-12 family cytokines on NK92 cells

Material type: 博士論文

Author: 大島, 隆志

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Name of awarding university/degree: 大阪歯科大学,博士（歯学）

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Note (General)：: We investigated the effect of IL-12 family cytokines (IL-12, IL-23, IL-27 and IL-35) on NK92 cells. We confirmed that NK92 cells are classified as sub...

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Material Type: 博士論文
Title: Effect of IL-12 family cytokines on NK92 cells
Author/Editor: 大島, 隆志
Author Heading: 大島, 隆志
Alternative Title: IL-12 ファミリーサイトカインの NK92 細胞に対する影響について
Degree grantor/type: 大阪歯科大学
Date Granted: 2018-03-29
Dissertation Number: 乙第1610号
Degree Type: 博士（歯学）
Text Language Code: eng
Subject Heading: Interleukin-12 family cytokines｜NK cells
Target Audience: 一般
Note (General): We investigated the effect of IL-12 family cytokines (IL-12, IL-23, IL-27 and IL-35) on NK92 cells. We confirmed that NK92 cells are classified as subpopulations of CD56bright CD16-. We measured the intracellular granules and cytokines by flow cytometry. We could not observe the effect of IL-12 family cytokines (IL-23, IL-27 and IL-35) other than IL-12 in perforin 1 and IFN-γ production. A small amount of granzyme B production was detected by stimulation of IL-12, IL-27 or IL-35. These results suggested the possibility that IL-27 or IL-35 has an effect on granzyme B production of NK92 cells.
2017年度
Source: fulltext
https://osaka-dent.repo.nii.ac.jp/?action=repository_action_common_download&item_id=197&item_no=1&attribute_id=20&file_no=2
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https://osaka-dent.repo.nii.ac.jp/?action=repository_action_common_download&item_id=197&item_no=1&attribute_id=20&file_no=1
Access Restrictions: インターネット公開
Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）
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Original Data Provider (Database): 大阪歯科大学 : 大阪歯科大学学術リポジトリ