Lung Cancer Risk in Passive Smokers using Salivary Exosome-Derived MicroRNAs

Material type: 博士論文

Author: 井戸垣, 潤

Publisher: -

Publication date: -

Material Format: Digital

Capacity, size, etc.: -

Name of awarding university/degree: 大阪歯科大学,博士（歯学）

View All

Notes on use

Note (General)：: The objective of this study was to investigate the lung cancer risk in passive smokers using salivary exosome-derived microRNAs (mirs). Individuals we...

Search by Bookstore

Holdings of Libraries in Japan

This page shows libraries in Japan other than the National Diet Library that hold the material.

List of Cooperating Institutions and Databases

Please contact your local library for information on how to use materials or whether it is possible to request materials from the holding libraries.

other

Osaka Dental University Academic Repository
Digital
You can check the holdings of institutions and databases with which Institutional Repositories DataBase(IRDB)(Institutional Repository) is linked at the site of Institutional Repositories DataBase(IRDB)(Institutional Repository).
Osaka Dental University Academic Repository

Search by Bookstore

Bibliographic Record

You can check the details of this material, its authority (keywords that refer to materials on the same subject, author's name, etc.), etc.

Digital

Material Type: 博士論文
Title: Lung Cancer Risk in Passive Smokers using Salivary Exosome-Derived MicroRNAs
Author/Editor: 井戸垣, 潤
Author Heading: 井戸垣, 潤
Alternative Title: 唾液中エクソソーム由来マイクロRNAを用いた受動喫煙者の肺がんリスク調査
Degree grantor/type: 大阪歯科大学
Date Granted: 2019-03-08
Dissertation Number: 甲第842号
Degree Type: 博士（歯学）
Text Language Code: eng
Subject Heading: carbon monoxide｜ microRNA｜ passive smoke｜ lung cancer risk｜ salivary exosomes
Target Audience: 一般
Note (General): The objective of this study was to investigate the lung cancer risk in passive smokers using salivary exosome-derived microRNAs (mirs). Individuals were confirmed to be passive smokers by inter-viewing them using the Kano Test for Social Nicotine Dependence (KTSND) and measuring exhaled breath carbon monoxide (eBCO) level. Unstimulated saliva samples were collected from 25 students, and exosomes were isolated from salivary supernatants. Total RNA was isolated from the isolated exosome and washed and spun repeatedly using a filter cartridge to obtain the total RNA. Digital PCR was performed using mir-22, mir-150, and mir-155, which are related to lung cancer; mir-191 was used as the endogenous control. Salivary exosome samples considered posi-tive by the carbon monoxide breath analysis monitor exhibited expression of mir-22, mir-150, and mir-155, that reportedly have increased expression in lung cancer. These findings indicate the possibility of investigating lung cancer risk in passive smokers using salivary exosome-derived mirs.
2018年度
Source: fulltext
https://osaka-dent.repo.nii.ac.jp/?action=repository_action_common_download&item_id=214&item_no=1&attribute_id=20&file_no=2
fulltext
https://osaka-dent.repo.nii.ac.jp/?action=repository_action_common_download&item_id=214&item_no=1&attribute_id=20&file_no=1
Access Restrictions: インターネット公開
Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）
https://irdb.nii.ac.jp
Original Data Provider (Database): 大阪歯科大学 : 大阪歯科大学学術リポジトリ