Comparison of histomorphometry and microCT after sinus augmentation using xenografts of different particle sizes in rabbits

• Material Type: 博士論文
• Title: Comparison of histomorphometry and microCT after sinus augmentation using xenografts of different particle sizes in rabbits
• Author/Editor: 飯田, 高久
• Author Heading: 飯田, 高久
• Alternative Title: ウサギによる大きさの異なる顆粒状異種他家骨による上顎洞底挙上術後の組織形態学的検討とμCTとの比較研究
• Degree grantor/type: 大阪歯科大学
• Date Granted: 2020-03-06
• Dissertation Number: 甲第879号
• Degree Type: 博士（歯学）
• Text Language Code: eng
• Subject Heading: animal study; sinus floor elevation; bone healing; xenograft; MicroCT analysis
• Target Audience: 一般
• Note (General): Purpose: The aim of the present experiment was to compare the data on new bone formation measured histologically and microtomographically in maxillary sinuses augmented with a xenograft with higher density and higher mineral content compared to the natural bone. The hypothesis was that histomorphometric and microCT analyses does not yield similar outcomes when a xenograft with higher density and mineral content compared to the natural bone is used.Methods: In 18 rabbits, the maxillary sinus was augmented bilaterally using deproteinized bovine bone mineral (DBBM) xenograft granules of either 0.125-1 mm or 1-2 mm of dimensions. The rabbits were euthanized after 2, 4, and 8 weeks of healing. Comparisons were performed between MicroCT and histological analyses.Results: After 2 weeks of healing, higher contents of bone were found at the histological compared to the MicroCT analyses in both sinuses, especially in the middle regions of the grafted sinus. Between 2 and 8 weeks of healing, new bone increased of about 21% at the histological analyses while, at the MicroCT, increased only about 4%. In the same period, the xenograft proportion decreased from 51.6±4.9% to 45.3±3.3% at the histological analyses while, at the MicroCT, the xenograft appeared to increase in percentages.Conclusion: Histological and microCT analyses yielded different outcomes when a xenograft with higher density and higher mineral content compared to the natural bone was used.; 2019年度
• Access Restrictions: インターネット公開
• Rights (production): CC BY-NC-ND
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 大阪歯科大学 : 大阪歯科大学学術リポジトリ

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