Elucidation of the Mechanism of Bone Regeneration When a Mixture of β-TCP and Autologous Bone Granules are Transplanted

• Material Type: 博士論文
• Title: Elucidation of the Mechanism of Bone Regeneration When a Mixture of β-TCP and Autologous Bone Granules are Transplanted
• Author/Editor: 辰村, 正泰
• Author Heading: 辰村, 正泰
• Alternative Title: β-TCP顆粒と自家骨顆粒を組み合わせた再生骨における骨再生のメカニズム解明
• Degree grantor/type: 大阪歯科大学
• Date Granted: 2021-03-05
• Dissertation Number: 甲第908号
• Degree Type: 博士（歯学）
• Text Language Code: eng
• Subject Heading: autologous bone graft; β-TCP granules; micro-CT; picrosirius red staining; col-lagen; vWF immunostaining
• Target Audience: 一般
• Note (General): We examined the amount and maturity of collagen as a parameter for bone quality in the graft material transplanted into a rat skull bone defect model. Male SD rats were used to generate an experimental animal model of skull defects. The obtained autologous bone granules and β-TCP granules were mixed at a ratio of 1:1 to prepare a graft material that combines autologous bone with β-TCP granules. At 8 weeks after transplantation, the β-TCP+ autologous bone and the autologous bone groups showed BV/TV values, measured based on CT image analysis, significantly different from those in the β-TCP and control groups. The β-TCP+ autologous bone group exhibited the ability to form blood vessels into the graft material for a longer period of time after transplantation compared to that in the autologous bone group, as well as the elevated production of collagen into β-TCP granules during the bone formation process compared to that in the β-TCP group.; 2020年度
• Access Restrictions: インターネット公開
• Rights (production): CC BY-NC-ND
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 大阪歯科大学 : 大阪歯科大学学術リポジトリ

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