Effects of amelogenin peptide derived from enamel matrix derivative on human dental pulp stem cells

Digital data available（大阪歯科大学学術リポジトリ）

学術機関リポジトリデータベース（IRDB）（機関リポジトリ）

Effects of amelogenin peptide derived from enamel matrix derivative on human dental pulp stem cells

Material type: 博士論文

Author: 中野, 裕司

Publisher: -

Publication date: -

Material Format: Digital

Capacity, size, etc.: -

Name of awarding university/degree: 大阪歯科大学,博士（歯学）

View All

Notes on use

Note (General)：: Dental pulp stem cells (DPSCs) play an important role in the homeostasis of the pulp tissue and have a high potential for osteogenic differentiation. ...

Search by Bookstore

Holdings of Libraries in Japan

This page shows libraries in Japan other than the National Diet Library that hold the material.

List of Cooperating Institutions and Databases

Please contact your local library for information on how to use materials or whether it is possible to request materials from the holding libraries.

other

Osaka Dental University Academic Repository
Digital
You can check the holdings of institutions and databases with which Institutional Repositories DataBase(IRDB)(Institutional Repository) is linked at the site of Institutional Repositories DataBase(IRDB)(Institutional Repository).
Osaka Dental University Academic Repository

Search by Bookstore

Bibliographic Record

You can check the details of this material, its authority (keywords that refer to materials on the same subject, author's name, etc.), etc.

Digital

Material Type: 博士論文
Title: Effects of amelogenin peptide derived from enamel matrix derivative on human dental pulp stem cells
Author/Editor: 中野, 裕司
Author Heading: 中野, 裕司
Alternative Title: ヒト歯髄幹細胞に対するエナメルマトリックスデリバティブ由来アメロジェニンペプチドの影響
Degree grantor/type: 大阪歯科大学
Date Granted: 2022-09-28
Dissertation Number: 乙第1642号
Degree Type: 博士（歯学）
Text Language Code: eng
Subject Heading: Enamel matrix derivative
Amelogenin
Dental pulp stem cells
Target Audience: 一般
Note (General): Dental pulp stem cells (DPSCs) play an important role in the homeostasis of the pulp tissue and have a high potential for osteogenic differentiation. Enamel matrix derivative (EMD) has been used in periodontal regeneration therapy. Previously, we designed a synthetic amelogenin peptide (AP) derived from EMD. In this study, we investigated the effects of AP on DPSCs and evaluated its usefulness as a dental pulp capping material. DPSCs were cultured in medium supplemented with AP (0 and 100 ng/ml) to examine the effect of DPSCs on cell morphology and the cell migration ability. In addition, DPSCs were cultured with osteogenic medium supplemented with AP at 0 and 100 ng/ml, and their osteogenic differentiation was examined by Alizarin Red staining. AP promoted cell extension by altering cell morphology, and also significantly promoted DPSCs chemotaxis and cell migration. Moreover, the number of calcified nodule formations stained by Alizarin Red increased in the AP group. In summary, AP may be useful as a dental pulp capping material.
2022年度
Source: fulltext
https://osaka-dent.repo.nii.ac.jp/?action=repository_action_common_download&item_id=339&item_no=1&attribute_id=20&file_no=2
fulltext
https://osaka-dent.repo.nii.ac.jp/?action=repository_action_common_download&item_id=339&item_no=1&attribute_id=20&file_no=1
Access Restrictions: インターネット公開
Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）
https://irdb.nii.ac.jp
Original Data Provider (Database): 大阪歯科大学 : 大阪歯科大学学術リポジトリ