The application of tetanic stimulation of the unilateral tibial nerve before transcranial stimulation can augment the amplitudes of myogenic motor-evoked potentials from the muscles in the bilateral upper and lower limbs.

• Material Type: 博士論文
• Title: The application of tetanic stimulation of the unilateral tibial nerve before transcranial stimulation can augment the amplitudes of myogenic motor-evoked potentials from the muscles in the bilateral upper and lower limbs.
• Author/Editor: Hayashi, Hironobu; Kawaguchi, Masahiko; Yamamoto, Yuri; Inoue, Satoki; Koizumi, Munehisa; Ueda, Yurito; Takakura, Yoshinori; Furuya, Hitoshi
• Author Heading: Hayashi, Hironobu; Kawaguchi, Masahiko; Yamamoto, Yuri; Inoue, Satoki; Koizumi, Munehisa; Ueda, Yurito; Takakura, Yoshinori; Furuya, Hitoshi
• Publication, Distribution, etc.: Lippincott, Williams & Wilkins
• Publication Date: 2008-07
• Publication Date (W3CDTF): 2008-07
• Periodical title: Anesthesia and analgesia
• No. or year of volume/issue: 107 1
• Volume: 107
• Issue: 1
• Pages: 215-220
• ISSN (Periodical Title): ISSN : 0003-2999
• Degree grantor/type: 奈良県立医科大学
• Date Granted: 2013-07-22
• Dissertation Number: 乙第1317号
• Degree Type: 博士（医学）
• Text Language Code: eng
• Subject Heading: motor evoked potentials; monitoring; tetanic stimulation; nerve; spinal cord
• Target Audience: 一般
• Note (General): type:Thesis; BACKGROUND: Recently, we reported a new technique to augment motor-evoked potentials (MEPs) under general anesthesia, posttetanic MEP (p-MEP), in which tetanic stimulation of the peripheral nerve before transcranial stimulation enlarged amplitudes of MEPs from the muscle innervated by the nerve subjected to tetanic stimulation. In the present study, we tested whether tetanic stimulation of the left tibial nerve can also augment amplitudes of MEPs from the muscles which are not innervated by the nerve subjected to tetanic stimulation. METHODS: Thirty patients undergoing spinal surgery under propofol-fentanyl anesthesia with partial neuromuscular blockade were examined. For conventional MEP (c-MEP) recording, transcranial stimulation with train-of-five pulses was delivered to C3-4, and the compound muscle action potentials were bilaterally recorded from the abductor pollicis brevis, abductor hallucis (AH), tibialis anterior, and soleus muscles. For p-MEP recording, tetanic stimulation (50 Hz, 50 mA of stimulus intensity) with a duration of 5 s was applied to the left tibial nerve at the ankle 1 s before transcranial stimulation. Transcranial stimulation and recording of compound muscle action potentials were performed in the same manner as c-MEP recording. Amplitudes of c-MEP and p-MEP were compared using Wilcoxon's signed rank test. RESULTS: Amplitudes of p-MEPs from the left AH muscle innervated by the left tibial nerve with tetanic stimulation were significantly larger compared with those of c-MEPs. Amplitudes of p-MEPs from the bilateral abductor pollicis brevis and soleus muscles and right AH and tibialis anterior muscles, which were not innervated by the left tibial nerve with tetanic stimulation, were also significantly larger compared with those of c-MEPs. CONCLUSION: In patients under propofol and fentanyl anesthesia with partial neuromuscular blockade, the application of tetanic stimulation to the left tibial nerve augmented the amplitudes of MEPs from the muscles without tetanic nerve stimulation and those with stimulation.; 博士（医学）・乙第1317号・平成25年7月22日; identifier:Anesthesia and analgesia vol.107 No.1 p.215-220; identifier:00032999; identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/2639; identifier:Anesthesia and analgesia, 107(1): 215-220
• Access Restrictions: インターネット公開
• Related Material (DOI): 10.1213/ane.0b013e318177082e
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 奈良県立医科大学 : 奈良県立医科大学機関リポジトリ GINMU

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http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/2639/1/01%e6%9c%ac%e6%96%87%e3%81%ae%e8%a6%81%e6%97%a8.pdf fulltext

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