Sentinel Lymph Node Detection in Patients with Oral Cancer by MR Lymphography using Superparamagnetic Iron Oxide.

• Material Type: 博士論文
• Title: Sentinel Lymph Node Detection in Patients with Oral Cancer by MR Lymphography using Superparamagnetic Iron Oxide.
• Author/Editor: Uemura, Hirokazu; Ota, Ichiro; Fujii, Takashi; Suzuki, Motoyuki; Sakai, Mio; Nakanishi, Katsuyuki; Tomita, Yasuhiko; Noguchi, Atsushi; Hosoi, Hiroshi; Yoshino, Kunitoshi
• Author Heading: Uemura, Hirokazu; Ota, Ichiro; Fujii, Takashi; Suzuki, Motoyuki; Sakai, Mio; Nakanishi, Katsuyuki; Tomita, Yasuhiko; Noguchi, Atsushi; Hosoi, Hiroshi; Yoshino, Kunitoshi
• Publication, Distribution, etc.: Bentham Open
• Publication Date: 2013-01
• Publication Date (W3CDTF): 2013-01
• Alternative Title: 超常磁性体を用いたMRリンフォグラフィーによる口腔癌患者のセンチネルリンパ節同定
• Periodical title: Open Otorhinolaryngology Journal
• No. or year of volume/issue: 7
• Volume: 7
• Pages: 14-18
• ISSN (Periodical Title): ISSN : 1874-4281
• Degree grantor/type: 奈良県立医科大学
• Date Granted: 2014-03-17
• Dissertation Number: 甲第622号
• Degree Type: 博士（医学）
• Text Language Code: eng
• Subject Heading: Head and neck cancer; sentinel lymph node; superparamagnetic iron oxide; MR lymphography
• Target Audience: 一般
• Note (General): type:Thesis; The purpose of this study was to examine the feasibility of interstitial MR lymphography using Superparamagnetic Iron Oxide (SPIO) to detect sentinel lymph nodes (SLNs) in head and neck cancer. For two patients with cT2N0 squamous cell carcinoma of the tongue, the submucosal injection of SPIO as well as sentinel lymph node navigation surgery (SLNNS) was performed before undergoing surgical treatment. SPIO was used for MR lymphography and Tc-99m phytate for SPECT. We compared the images by both modalities. Berlin blue stain was also performed postoperatively if SLNs had the uptake of SPIO. The lymph nodes with MR signal attenuation and those with hot spots were probed to be anatomically identical. All the lymph nodes detected as a SLN by a gamma-probe contained the blue granules from SPIO. These data suggest that SPIO can be a novel tracer for performing SLNNS and SLN biopsy in oral cancer patients with cN0 neck.; 博士（医学）・甲622号・平成26年3月17日; identifier:Open Otorhinolaryngology Journal Vol.7 p.14-18; identifier:18744281; identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/2707; identifier:Open Otorhinolaryngology Journal, 7: 14-18
• Source: fulltext; http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/2707/1/01%e6%9c%ac%e6%96%87%e3%81%ae%e8%a6%81%e6%97%a8.pdf; http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/2707/2/02%e5%af%a9%e6%9f%bb%e8%a6%81%e6%97%a8.pdf; http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/2707/3/03%e6%9c%ac%e6%96%87.pdf
• Access Restrictions: インターネット公開
• Related Material (DOI): 10.2174/1874428120131206002
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 奈良県立医科大学 : 奈良県立医科大学機関リポジトリ GINMU