Association of Visual Acuity and Cognitive Impairment in Older Individuals: Fujiwara-kyo Eye Study.

• Material Type: 博士論文
• Title: Association of Visual Acuity and Cognitive Impairment in Older Individuals: Fujiwara-kyo Eye Study.
• Author/Editor: Mine, Masashi; Miyata, Kimie; Morikawa, Masayuki; Nishi, Tomo; Okamoto, Nozomi; Kawasaki, Ryo; Yamashita, Hidetoshi; Kurumatani, Norio; Ogata, Nahoko
• Author Heading: Mine, Masashi; Miyata, Kimie; Morikawa, Masayuki; Nishi, Tomo; Okamoto, Nozomi; Kawasaki, Ryo; Yamashita, Hidetoshi; Kurumatani, Norio; Ogata, Nahoko
• Publication, Distribution, etc.: Mary Ann Liebert, Inc.
• Publication Date: 2016-08-01
• Publication Date (W3CDTF): 2016-08-01
• Alternative Title: 高齢者における視機能と認知機能障害の関連 : 藤原京アイスタディより
• Periodical title: BioResearch open access
• No. or year of volume/issue: 5 1
• Volume: 5
• Issue: 1
• Pages: 228-234
• ISSN (Periodical Title): ISSN : 2164-7860
• Degree grantor/type: 奈良県立医科大学
• Date Granted: 2017-03-15
• Dissertation Number: 乙第1396号
• Degree Type: 博士（医学）
• Text Language Code: eng
• Subject Heading: aging; neuroscience; regeneration
• Target Audience: 一般
• Note (General): type:Thesis; Both visual impairment and cognitive impairment are essential factors that determine the quality of life in the aged population. The aim of this study was to determine if a correlation existed between visual acuity and cognitive impairment in an elderly Japanese population. The Fujiwara-kyo Eye Study was a cross-sectional study of individuals aged ≥68 years who lived in Nara Prefecture of Japan. Participants underwent ophthalmological examinations and cognitive function test. A mild visual impairment was defined as having a best corrected visual acuity (BCVA) >0.2 logarithm of the minimum angle of resolution (logMAR) units in the better eye. Cognitive impairment was defined as having a Mini-Mental State Examination (MMSE) score of ≤23 points. A total to 2818 individuals completed the examinations. The mean age of the participants was 76.3 ± 4.8 years (mean ± standard deviation). The mean BCVA of the better eye was -0.02 ± 0.13 logMAR units and 6.6% subjects were classified as being mildly visually impaired. The mean MMSE score was 27.3 ± 2.3 and 5.7% subjects were classified as being cognitively impaired. The proportion of subjects with cognitive or moderate visual impairment increased with age, and there was a significant correlation between the visual acuity and MMSE score (r = -0.10, p < 0.0001). Subjects with mild visual impairments had 2.4 times higher odds of having cognitive impairment than those without visual impairment (odds ratio 2.4, 95% confidence interval, 1.5-3.8, p < 0.001) after adjusting for age, sex, and length of education. We conclude that it may be important to maintain good visual acuity to reduce the risk of having cognitive impairment.; 博士（医学）・乙第1396号・平成29年3月15日; © Masashi Mine et al. 2016; Published by Mary Ann Liebert, Inc. This Open Access article is distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.; identifier:BioResearch open access Vol.5 No.1 p.228-234 (2016 Aug); identifier:21647860; identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/3329; identifier:BioResearch open access, 5(1): 228-234
• Source: fulltext; http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3329/1/01_%e4%b9%991396%e6%9c%ac%e6%96%87%e3%81%ae%e8%a6%81%e6%97%a8.pdf; http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3329/2/02_%e4%b9%991396%e5%af%a9%e6%9f%bb%e8%a6%81%e6%97%a8.pdf; http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3329/3/03_%e4%b9%991396%e6%9c%ac%e6%96%87.pdf
• Access Restrictions: インターネット公開
• Related Material (DOI): 10.1089/biores.2016.0023
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 奈良県立医科大学 : 奈良県立医科大学機関リポジトリ GINMU