Correlation between the ABC classification and radiological findings for assessing gastric cancer risk.

• Material Type: 博士論文
• Title: Correlation between the ABC classification and radiological findings for assessing gastric cancer risk.
• Author/Editor: Itoh, Takahiro; Saito, Miho; Marugami, Nagaaki; Hirai, Toshiko; Marugami, Aki; Takahama, Junko; Tanaka, Toshihiro; Kichikawa, Kimihiko
• Author Heading: Itoh, Takahiro; Saito, Miho; Marugami, Nagaaki; Hirai, Toshiko; Marugami, Aki; Takahama, Junko; Tanaka, Toshihiro; Kichikawa, Kimihiko
• Publication, Distribution, etc.: Japan Radiological Society / Springer Japan
• Publication Date: 2015-10
• Publication Date (W3CDTF): 2015-10
• Alternative Title: 胃がんリスク評価におけるABC分類とX線所見の関連性について
• Periodical title: Japanese journal of radiology
• No. or year of volume/issue: 33 10
• Volume: 33
• Issue: 10
• Pages: 636-644
• ISSN (Periodical Title): ISSN : 1867-1071
• Degree grantor/type: 奈良県立医科大学
• Date Granted: 2015-11-27
• Dissertation Number: 乙第1370号
• Degree Type: 博士（医学）
• Text Language Code: eng
• Subject Heading: Helicobacter pylori; ABC classification; Gastric cancer; Radiological finding
• Target Audience: 一般
• Note (General): type:Thesis; PURPOSE:To investigate the correlation between ABC risk assessment and radiological findings of gastric mucosa and to propose an improved method for gastric cancer screening. MATERIALS AND METHODS:We evaluated 318 participants with Helicobacter pylori (Hp) antibody titers, serum pepsinogen (PG) and upper GI radiography and then classified them into three groups: A, double-negative; B, Hp-positive, PG-negative; C, PG-positive. Group A was subclassified as: A-1, Hp antibody titer <3.0 U/ml; A-2, Hp antibody titer ≥3.0 U/ml. Results for group A and non-A (B or C) participants and radiological findings of gastric mucosa (fold and area gastricae) were analyzed retrospectively. RESULTS:Radiological findings differed significantly between the 207 A-1 and 98 non-A group. Odds ratios were 17.72 for fold distribution, 10.63 for fold thickness, 6.10 for fold characteristics, and 10.62 for area gastricae. Presence of ≥2 risk factors offered 90.3 % sensitivity, 94.7 % specificity, and 93.3 % accuracy. Nine (69.2 %) of the 13 A-2 group participants and 11 (5.3 %) A-1 group participants had a risk for gastric cancer according to radiological findings. CONCLUSION:A good correlation exists between ABC classifications and radiological findings for gastric cancer risk, but some discrepant cases exist. We recommend both methods as screening for gastric cancer.; 博士（医学）・乙第1370号・平成27年11月27日; © Japan Radiological Society 2015; © Springer-Verlag Berlin Heidelberg 2015; The final publication is available at Springer via http://dx.doi.org/10.1007/s11604-015-0469-3; identifier:Japanese journal of radiology Vol.33 No.10 p.636-644 (2015.10); identifier:18671071; identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/3108; identifier:Japanese journal of radiology, 33(10): 636-644
• Source: fulltext; http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3108/1/01_%e4%b9%991370%e6%9c%ac%e6%96%87%e3%81%ae%e8%a6%81%e6%97%a8.pdf; http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3108/2/02_%e4%b9%991370%e5%af%a9%e6%9f%bb%e8%a6%81%e6%97%a8.pdf; http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3108/6/03_%e4%b9%991370%e6%9c%ac%e6%96%87.pdf; http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3108/7/04_%e4%b9%991370Figure_1-5.pdf; http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3108/8/05_%e4%b9%991370Table1_1-5.pdf
• Access Restrictions: インターネット公開
• Related Material (DOI): 10.1007/s11604-015-0469-3
• Periodical Title (NCID): AA12375935; https://ci.nii.ac.jp/ncid/AA12375935
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 奈良県立医科大学 : 奈良県立医科大学機関リポジトリ GINMU