Dexamethasone added to levobupivacaine prolongs the duration of interscalene brachial plexus block and decreases rebound pain after arthroscopic rotator cuff repair.

• Material Type: 博士論文
• Title: Dexamethasone added to levobupivacaine prolongs the duration of interscalene brachial plexus block and decreases rebound pain after arthroscopic rotator cuff repair.
• Author/Editor: Morita, Shuzo; Oizumi, Naomi; Suenaga, Naoki; Yoshioka, Chika; Yamane, Shintaro; Tanaka, Yasuhito
• Author Heading: Morita, Shuzo; Oizumi, Naomi; Suenaga, Naoki; Yoshioka, Chika; Yamane, Shintaro; Tanaka, Yasuhito
• Publication, Distribution, etc.: Elsevier
• Publication Date: 2020-09
• Publication Date (W3CDTF): 2020-09
• Alternative Title: 鏡視下腱板修復術の斜角筋間腕神経叢ブロックにおいて、レボブピバカインにデキサメサゾンを加えると鎮痛時間が延長するのみならず、術後リバウンドペインが減少する。
• Periodical title: Journal of shoulder and elbow surgery
• No. or year of volume/issue: 29 9
• Volume: 29
• Issue: 9
• Pages: 1751-1757
• ISSN (Periodical Title): ISSN : 1058-2746
• Degree grantor/type: 奈良県立医科大学
• Date Granted: 2020-12-24
• Dissertation Number: 甲第759号
• Degree Type: 博士（医学）
• Text Language Code: und
• Subject Heading: Interscalene brachial plexus block; dexamethasone; arthroscopic rotator cuff repair; postoperative analgesia; rebound pain; shoulder surgery
• Target Audience: 一般
• Note (General): type:Thesis; Background: It has been reported that the addition of dexamethasone to interscalene brachial plexus block (ISBPB) prolongs the duration of the block effect. However, there have been no studies focusing on the effects of dexamethasone on rebound pain after the block effect has worn off. The aim of this study was to investigate the effect on postoperative pain when dexamethasone was added to ISBPB for arthroscopic rotator cuff repair (ARCR). Methods: In this multicenter, single-blinded, and randomized controlled study, 54 patients (33 males, 21 females) who received ARCR were randomly assigned to group L (ISBPB with 20 cc of 0.25% levobupivacaine; 21 patients) or group LD (ISBPB with 20 cc of 0.25% levobupivacaine + 3.3 mg dexamethasone; 33 patients). The primary outcome was the visual analog scale (VAS) for pain after the block effect had worn off. Secondary outcomes were the duration of analgesia, the time to the first request for additional analgesic, the number of additional doses of analgesic, and complications. Results: The VAS scores on postoperative days 0 and 1 were significantly lower in group LD than group L (P = .005, .035). This indicated that the rebound pain was relieved in group LD. After postoperative day 1, there was no significant difference in VAS score (P = .43 and .19 for days 2 and 3, respectively). The duration of analgesia was significantly longer in group LD than group L (P < .001). The time to the first request for additional analgesic was significantly longer in group LD than group L (P < .001). The number of additional doses of analgesic was significantly lower in group LD (P < .001). Conclusion: In ARCR, the addition of dexamethasone to levobupivacaine not only prolongs the duration of ISBPB but also relieves rebound pain after the block effect wears off.; 博士（医学）・甲第759号・令和2年12月24日; Copyright © 2020 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc. All rights reserved.; identifier:Journal of shoulder and elbow surgery Vol.29 No.9 p.1751-1757 (2020 Sep); identifier:10582746; identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/3817; identifier:Journal of shoulder and elbow surgery, 29(9): 1751-1757
• Source: fulltext; http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3817/1/01%e7%94%b2759%e6%9c%ac%e6%96%87%e3%81%ae%e8%a6%81%e6%97%a8.pdf; http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3817/2/02%e7%94%b2759%e5%af%a9%e6%9f%bb%e8%a6%81%e6%97%a8.pdf; http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3817/3/03%e7%94%b2759%e6%9c%ac%e6%96%87.pdf
• Access Restrictions: インターネット公開
• Related Material (DOI): 10.1016/j.jse.2020.04.019
• Periodical Title (NCID): AA10826771; https://ci.nii.ac.jp/ncid/AA10826771
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 奈良県立医科大学 : 奈良県立医科大学機関リポジトリ GINMU