Motor evoked potential monitoring can evaluate ischemic tolerance to carotid artery occlusion during surgery.

• Material Type: 博士論文
• Title: Motor evoked potential monitoring can evaluate ischemic tolerance to carotid artery occlusion during surgery.
• Author/Editor: Takamura, Yoshiaki; Motoyama, Yasushi; Takatani, Tsunenori; Takeshima, Yasuhiro; Matsuda, Ryosuke; Tamura, Kentaro; Yamada, Shuichi; Nishimura, Fumihiko; Nakagawa, Ichiro; Park, Young-Su; Nakase, Hiroyuki
• Author Heading: Takamura, Yoshiaki; Motoyama, Yasushi; Takatani, Tsunenori; Takeshima, Yasuhiro; Matsuda, Ryosuke; Tamura, Kentaro; Yamada, Shuichi; Nishimura, Fumihiko; Nakagawa, Ichiro; Park, Young-Su; Nakase, Hiroyuki
• Publication, Distribution, etc.: Springer Nature
• Publication Date: 2020-07-31
• Publication Date (W3CDTF): 2020-07-31
• Alternative Title: 術中運動誘発電位モニタリングによる内頚動脈閉塞に対する虚血耐性評価
• Periodical title: Journal of clinical monitoring and computing
• No. or year of volume/issue: 35 5
• Volume: 35
• Issue: 5
• Pages: 1055-1062
• ISSN (Periodical Title): ISSN : 1387-1307
• Degree grantor/type: 奈良県立医科大学
• Date Granted: 2020-12-24
• Dissertation Number: 乙第1483号
• Degree Type: 博士（医学）
• Text Language Code: eng
• Subject Heading: Balloon test occlusion; Carotid artery occlusion; Intraoperative neurophysiological monitoring; Ischemic tolerance; Motor evoked potential
• Target Audience: 一般
• Note (General): type:Thesis; Balloon test occlusion (BTO) is a useful examination for evaluating ischemic tolerance to internal carotid artery (ICA) occlusion. The aim of this study was to investigate the relationships between intraoperative motor evoked potential (MEP) monitoring and the results of preoperative BTO. Between 2013 and 2017, 32 patients undergoing surgery under general anesthesia with intraoperative MEP monitoring, in whom preoperative BTO was performed, were identified. A receiver operator characteristic (ROC) analysis was performed to determine the appropriate cutoff value of MEP amplitude for BTO-positive. Furthermore, the accuracy of MEP monitoring for BTO-positive was compared with electroencephalogram (EEG) and somatosensory evoked potential (SEP) monitoring. Four of 32 (12.5%) patients were BTO-positive. The cutoff value of MEP amplitude for BTO-positive was a > 80% reduction from the baseline level, which showed sensitivity of 100% and specificity of 100%. Thus, the sensitivity and specificity for BTO-positive were significantly higher for MEP than for EEG (100% and 72.0%, p = 0.02) in 28 patients, but they were not significantly different compared with SEP (33.3% and 100%, p = 0.48) in 21 patients. MEP monitoring might be one of the alternatives for evaluating ischemic tolerance to ICA occlusion during surgery. The cutoff value of MEP amplitude was a > 80% reduction.; 博士（医学）・乙第1483号・令和2年12月24日; © Springer Nature B.V. 2020; This is a post-peer-review, pre-copyedit version of an article published in Journal of clinical monitoring and computing. The final authenticated version is available online at: http://dx.doi.org/10.1007/s10877-020-00573-0.; identifier:Journal of clinical monitoring and computing Vol.35 No.5 p.1055-1062 (2021 Oct); identifier:13871307; identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/3828; identifier:Journal of clinical monitoring and computing, 35(5): 1055-1062
• Access Restrictions: インターネット公開
• Related Material (DOI): 10.1007/s10877-020-00573-0
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 奈良県立医科大学 : 奈良県立医科大学機関リポジトリ GINMU

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http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3828/1/01%e4%b9%991483%e6%9c%ac%e6%96%87%e3%81%ae%e8%a6%81%e6%97%a8.pdf fulltext

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3828/2/02%e4%b9%991483%e5%af%a9%e6%9f%bb%e8%a6%81%e6%97%a8.pdf fulltext

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3828/6/03%e4%b9%991483%e6%9c%ac%e6%96%87.pdf fulltext