A single amino acid substitution in the NS4B protein of Dengue virus confers enhanced virus growth and fitness in human cells in vitro through IFN-dependent host response

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A single amino acid substitution in the NS4B protein of Dengue virus confers enhanced virus growth and fitness in human cells in vitro through IFN-dependent host response

Material type: 博士論文

Author: Bui, Thu Thuy

Publisher: Microbiology Society

Publication date: 2018-09-20

Material Format: Digital

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Name of awarding university/degree: Nagasaki University (長崎大学),博士(医学)

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Note (General)：: 長崎大学学位論文学位記番号:博(医歯薬)甲第1098号学位授与年月日:平成30年9月20日Author: Thuy Thu Bui, Meng Ling Moi, Takeshi Nabeshima, Taichiro Takemura, Trang Thu Nguyen, Linh Ngoc ...

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Summary, etc.：: Dengue virus (DENV) replication between mosquito and human hosts is hypothesized to be associated with viral determinants that interact in a different...

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Material Type: 博士論文
Title: A single amino acid substitution in the NS4B protein of Dengue virus confers enhanced virus growth and fitness in human cells in vitro through IFN-dependent host response
Author/Editor: Bui, Thu Thuy
Author Heading: Bui, Thu Thuy
Publication, Distribution, etc.: Microbiology Society
Publication Date: 2018-09-20
Publication Date (W3CDTF): 2018-09-20
Alternative Title: デングウイルス非構造タンパク質NS4Bの一残基変異はヒト細胞においてインターフェロンの応答を抑制しウイルス増殖および適合性を増強する
Periodical title: Journal of General Virology
No. or year of volume/issue: 99 8
Volume: 99
Issue: 8
Pages: 1044-1057
ISSN (Periodical Title): ISSN : 00221317
ISSN : 14652099
Degree grantor/type: Nagasaki University (長崎大学)
Date Granted: 2018-09-20
Dissertation Number: 甲医歯薬第1098号
Degree Type: 博士(医学)
Text Language Code: eng
Subject Heading: Dengue virus
NS4B
variants
Target Audience: 一般
Note (General): 長崎大学学位論文学位記番号:博(医歯薬)甲第1098号学位授与年月日:平成30年9月20日
Author: Thuy Thu Bui, Meng Ling Moi, Takeshi Nabeshima, Taichiro Takemura, Trang Thu Nguyen, Linh Ngoc Nguyen, Hang Thi Thu Pham, Thi Thu Thuy Nguyen, Dao Huy Manh, Shyam Prakash Dumre, Shusaku Mizukami, Kenji Hirayama, Shigeru Tajima, Mai Thi Quynh Le, Kiyoshi Aoyagi, Futoshi Hasebe and Kouichi Morita
Citation: Journal of General Virology, 99(8), pp.1044-1057; 2018
Nagasaki University (長崎大学), 博士(医学) (2018-09-20)
Format (IMT): application/pdf
Source: ISYK1098_Bui.pdf （fulltext）
https://nagasaki-u.repo.nii.ac.jp/record/1323/files/ISYK1098_Bui.pdf
Access Restrictions: インターネット公開
Rights (production): c 2018 Microbiology Society
Related Material (DOI): 10.1099/jgv.0.001092
Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）
https://irdb.nii.ac.jp
Original Data Provider (Database): 長崎大学 : 長崎大学学術研究成果リポジトリ