Prevalence of and risk factors for depressive symptoms in non-tuberculous mycobacterial pulmonary disease

• Material Type: 博士論文
• Title: Prevalence of and risk factors for depressive symptoms in non-tuberculous mycobacterial pulmonary disease
• Author/Editor: 松村, 佑介
• Author Heading: 松村, 佑介
• Publication, Distribution, etc.: International Union Against Tuberculosis and Lung Disease
• Publication Date: 2023-03-20
• Publication Date (W3CDTF): 2023-03-20
• Alternative Title: 非結核性抗酸菌性肺疾患における抑うつ症状の有病率とその危険因子について
• Periodical title: The International Journal of Tuberculosis and Lung Disease
• No. or year of volume/issue: 26 4
• Volume: 26
• Issue: 4
• Pages: 310-316
• ISSN (Periodical Title): ISSN : 1027-3719; ISSN : 1815-7920
• Degree grantor/type: Nagasaki University (長崎大学)
• Date Granted: 2023-03-20
• Dissertation Number: 甲医歯薬第1490号
• Degree Type: 博士(医学)
• Text Language Code: eng
• Subject Heading: depressive symptoms; health-related quality of life; non-tuberculous mycobacterial pulmonary disease; sleep disturbance
• Target Audience: 一般
• Note (General): BACKGROUND: The presence of depressive symptoms in patients with non-tuberculous mycobacterial pulmonary disease (NTM-PD) is an important research topic; however, the prevalence of depressive symptoms and the factors that influence their development are unclear. OBJECTIVE: To analyse the association between CES-D (Center for Epidemiological Studies Depression Scale) scores and clinical parameters such as age, disease duration, pulmonary function, imaging findings, blood data, physical functions, sleep disturbances, respiratory symptoms and health-related quality of life (HRQOL). METHODS: We conducted a cross-sectional retrospective study of 114 patients with NTM-PD at a single centre from March 2016 to January 2021 to evaluate the relationship between CES-D scores and clinical parameters. RESULTS: Participants had a median age of 64 years; 32.5% of them had depressive symptoms. Disease duration, albumin, C-reactive protein, pulmonary function, dyspnoea, exercise capacity, respiratory symptoms, cough-related HRQOL and sleep disturbances were associated with depressive symptoms. Binomial logistic regression analyses indicated that the CES-D score was significantly associated with cough-related HRQOL and sleep disturbances. CONCLUSION: A high percentage of NTM-PD patients in this study experienced depressive symptoms, and these patients had abnormalities of various clinical parameters. Cough-related HRQOL and sleep disturbance had a strong influence on the development of depressive symptoms.; 長崎大学学位論文 学位記番号:博(医歯薬)甲第1490号 学位授与年月日:令和5年3月20日; Author: Matsumura, Y. ; Tabusadani, M. ; Yamane, K. ; Takao, S. ; Kuroyama, Y. ; Mori, K. ; Ono, K. ; Kawahara, K. ; Omatsu, S. ; Furuuchi, K. ; Fujiwara, K. ; Morimoto, K. ; Kimura, H. ; Senjyu, H; Citation: The International Journal of Tuberculosis and Lung Disease, 26(4), pp. 310-316; 2022; identifier:Nagasaki University (長崎大学), 博士(医学) (2023-03-20)
• Source: https://nagasaki-u.repo.nii.ac.jp/?action=repository_action_common_download&item_id=27998&item_no=1&attribute_id=70&file_no=1 （fulltext）; https://nagasaki-u.repo.nii.ac.jp/?action=repository_action_common_download&item_id=27998&item_no=1&attribute_id=70&file_no=1
• Access Restrictions: インターネット公開
• Rights (production): © 2022 The Union. This is the final version of the paper accepted for publicationin the IJTLD.
• Related Material: http://hdl.handle.net/10069/00042125
• Related Material (DOI): 10.5588/ijtld.21.0527
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 長崎大学 : 長崎大学学術研究成果リポジトリ