Evaluation of a Novel FKS1 R1354H Mutation Associated with Caspofungin Resistance in Candida auris Using the CRISPR-Cas9 System

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Evaluation of a Novel FKS1 R1354H Mutation Associated with Caspofungin Resistance in Candida auris Using the CRISPR-Cas9 System

Material type: 博士論文

Author: 清原, 舞子

Publisher: MDPI

Publication date: 2023-09-06

Material Format: Digital

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Name of awarding university/degree: Nagasaki University (長崎大学),博士(医学)

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Note (General)：: 長崎大学学位論文学位記番号:博(医歯薬)甲第1546号学位授与年月日:令和5年9月6日Author: Maiko Kiyohara, Taiga Miyazaki, Michiyo Okamoto, Tatsuro Hirayama, Koichi Makimura, Hiroji Chiban...

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Summary, etc.：: Outbreaks of invasive infections, with high mortality rates, caused by multidrug-resistant Candida auris have been reported worldwide. Although hotspo...

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Material Type: 博士論文
Title: Evaluation of a Novel FKS1 R1354H Mutation Associated with Caspofungin Resistance in Candida auris Using the CRISPR-Cas9 System
Author/Editor: 清原, 舞子
Author Heading: 清原, 舞子
Publication, Distribution, etc.: MDPI
Publication Date: 2023-09-06
Publication Date (W3CDTF): 2023-09-06
Alternative Title: Candida aurisにCRISPR-Cas9法を応用した、カスポファンギン耐性に関与する新たなFKS1 R1354H変異の評価
Periodical title: Journal of Fungi
No. or year of volume/issue: 9
Volume: 9
Pages: art. no. 529-
ISSN (Periodical Title): EISSN : 2309-608X
Degree grantor/type: Nagasaki University (長崎大学)
Date Granted: 2023-09-06
Dissertation Number: 甲医歯薬第1546号
Degree Type: 博士(医学)
Text Language Code: eng
Subject Heading: Candida auris
echinocandin
caspofungin
antifungal resistance
FKS1
CRISPR-Cas9
Target Audience: 一般
Note (General): 長崎大学学位論文学位記番号:博(医歯薬)甲第1546号学位授与年月日:令和5年9月6日
Author: Maiko Kiyohara, Taiga Miyazaki, Michiyo Okamoto, Tatsuro Hirayama, Koichi Makimura, Hiroji Chibana, Nana Nakada, Yuya Ito, Makoto Sumiyoshi, Nobuyuki Ashizawa, Kazuaki Takeda, Naoki Iwanaga, Takahiro Takazono, Koichi Izumikawa, Katsunori Yanagihara, Shigeru Kohno and Hiroshi Mukae
Citation: Journal of Fungi, 9, art. no. 529; 2023
Nagasaki University (長崎大学), 博士(医学) (2023-09-06)
Format (IMT): application/pdf
Source: fulltext
https://nagasaki-u.repo.nii.ac.jp/record/2000366/files/ISYK1546_Kiyohara.pdf
Access Restrictions: インターネット公開
Rights (production): © 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Related Material (URI): HDL
http://hdl.handle.net/10069/0002000217
Related Material (DOI): 10.3390/jof9050529
Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）
https://irdb.nii.ac.jp
Original Data Provider (Database): 長崎大学 : 長崎大学学術研究成果リポジトリ