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文書・図像類

WT1を標的とした急性骨髄性白血病のキメラ抗原受容体発現T細胞療法の基盤構築

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WT1を標的とした急性骨髄性白血病のキメラ抗原受容体発現T細胞療法の基盤構築

Material type
文書・図像類
Author
片山, 直之
Publisher
三重大学
Publication date
2020-05-15
Material Format
Digital
Capacity, size, etc.
-
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application/pdf2017年度~2019年度科学研究費補助金(基盤研究(C))研究成果報告書17K09923

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Summary, etc.:

免疫不全マウスへの異種移植系とin vitro培養系を用いて、CD25+急性骨髄性白血病においては白血病幹細胞分画のCD25の発現は変動することを明らかにし、CD25はCD25+急性骨髄性白血病の分子標的とはなり難いことが示した。成人B1細胞の起源を検討した。造血幹細胞に遺伝子異常を認めるが、その造...

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Digital

Material Type
文書・図像類
Author/Editor
片山, 直之
Author Heading
片山, 直之 カタヤマ, ナオユキ
Publication, Distribution, etc.
Publication Date
2020-05-15
Publication Date (W3CDTF)
2020-05-15
Alternative Title
Basic construction of WT1-targetting CAR-T therapy for acute myeloid leukemia
Text Language Code
jpn