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文書・図像類

小核移行トリガー蛋白質の探索と後天的トリソミックレスキューへの応用

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小核移行トリガー蛋白質の探索と後天的トリソミックレスキューへの応用

Material type
文書・図像類
Author
脇田, 幸子
Publisher
三重大学
Publication date
2020-05-20
Material Format
Digital
Capacity, size, etc.
-
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Note (General):

application/pdf2018年度~2019年度科学研究費補助金(挑戦的萌芽研究)研究成果報告書18K19513

Detailed bibliographic record

Summary, etc.:

小核移行トリガー蛋白質の特定は、二次元電気泳動法にて小核特異的蛋白質の分離に難航したため、CRISPR/Cas9を用いて標的染色体を特異的に切断、小核へ移行後、後天的トリソミックレスキューを誘導する方略に変更した。13箇所の切断で最もdisomy細胞が多く出現し、後天的トリソミックレスキューが誘導さ...

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Digital

Material Type
文書・図像類
Author/Editor
脇田, 幸子
Author Heading
脇田, 幸子 ワキタ, サチコ
Publication, Distribution, etc.
Publication Date
2020-05-20
Publication Date (W3CDTF)
2020-05-20
Alternative Title
Search for micronucleus migration trigger proteins and their application to acquired trisomic rescue
Text Language Code
jpn