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文書・図像類

癌間質と去勢抵抗性前立腺癌;スプライシングバリアント制御による新規治療戦略の開発

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癌間質と去勢抵抗性前立腺癌;スプライシングバリアント制御による新規治療戦略の開発

Material type
文書・図像類
Author
佐々木, 豪
Publisher
三重大学
Publication date
2020-05-14
Material Format
Digital
Capacity, size, etc.
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2018年度~2019年度科学研究費補助金(若手研究)研究成果報告書18K16690

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Summary, etc.:

去勢抵抗性前立腺癌(CRPC)において、血中循環前立腺癌細胞にアンドロゲン受容体スプライシングバリアント(ARVs)の発現が見られた場合、新規AR阻害薬も無効である。癌関連線維芽細胞(CAFs)を中心とする癌微小環境が、前立腺癌細胞の細胞内シグナルを活性化し、治療抵抗性ARVsの発現を誘導するという...

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Digital

Material Type
文書・図像類
Author/Editor
佐々木, 豪
Author Heading
佐々木, 豪 ササキ, タケシ
Publication, Distribution, etc.
Publication Date
2020-05-14
Publication Date (W3CDTF)
2020-05-14
Alternative Title
Effects of prostate cancer associated fibroblasts in the expression of aberrant andorgen splicing variants in prostate cancer cells
Text Language Code
jpn