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文書・図像類

悪性腫瘍におけるPDE2細胞内情報伝達複合体を標的とした新規個別化治療の探索

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悪性腫瘍におけるPDE2細胞内情報伝達複合体を標的とした新規個別化治療の探索

Material type
文書・図像類
Author
村田, 琢ほか
Publisher
三重大学
Publication date
2021-05-10
Material Format
Digital
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application/pdf2018年度~2020年度科学研究費補助金(基盤研究(C))研究成果報告書18K09720

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Summary, etc.:

Phosphodiesterase(PDE)は細胞内シグナル伝達物質であるcAMPやcGMPの分解酵素で細胞内の濃度を調整し、様々な生理作用に関係している。PDEはPDE1からPDE11 までの11種類のアイソザイムが存在する。これまでにわれわれはPDEのアイソザイムの一つであるPDE2が浸潤と関係...

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Digital

Material Type
文書・図像類
Author/Editor
村田, 琢
清水, 香澄
Author Heading
村田, 琢 ムラタ, タク
清水, 香澄 シミズ, カスミ
Publication, Distribution, etc.
Publication Date
2021-05-10
Publication Date (W3CDTF)
2021-05-10
Alternative Title
Search for novel personalized therapies targeting the PDE2 intracellular signaling complex in malignancies
Text Language Code
jpn