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口腔悪性黒色腫新治療薬の開発-PDE1阻害剤の臨床応用を目指して

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口腔悪性黒色腫新治療薬の開発-PDE1阻害剤の臨床応用を目指して

Material type
文書・図像類
Author
清水, 香澄ほか
Publisher
三重大学
Publication date
2021-05-19
Material Format
Digital
Capacity, size, etc.
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application/pdf2018年度~2020年度科学研究費補助金(基盤研究(C))研究成果報告書18K09765

Detailed bibliographic record

Summary, etc.:

実験に使用した高転移悪性黒色腫細胞株A375SMのPDEの発現について確認を行った結果、PDE1活性とPDE1C mRNAの発現を確認した。また、PDE5Aの発現はわずかで、以前の悪性黒色腫細胞株MAAのPDE発現の特徴と一致していた。  A375SM cellを眼窩静脈叢から移植し肺転移を確認した...

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Digital

Material Type
文書・図像類
Author/Editor
清水, 香澄
村田, 琢
Author Heading
清水, 香澄 シミズ, カスミ
村田, 琢 ムラタ, タク
Publication, Distribution, etc.
Publication Date
2021-05-19
Publication Date (W3CDTF)
2021-05-19
Alternative Title
Studies for clinical application of PDE1 inhibitors to the treatment of malignant melanoma
Text Language Code
jpn