CRISPR-mediated Bmpr2 point mutation exacerbates late pulmonary vasculopathy and reduces survival in rats with experimental pulmonary hypertension

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CRISPR-mediated Bmpr2 point mutation exacerbates late pulmonary vasculopathy and reduces survival in rats with experimental pulmonary hypertension

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Note (General)：: application/pdf本文/The Department of Anesthesiology and Critical Care Medicine, Mie University Graduate School of Medicine, 2‑174 Edobashi, Tsu city, M...

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Summary, etc.：: Background: Patients with pulmonary arterial hypertension (PAH) carrying bone morphogenetic protein receptor type 2 (Bmpr2) mutations present earlier ...

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Material Type: 博士論文
Title: CRISPR-mediated Bmpr2 point mutation exacerbates late pulmonary vasculopathy and reduces survival in rats with experimental pulmonary hypertension
Author/Editor: JANE, CHANDA KABWE
Author Heading: JANE, CHANDA KABWE
Publication, Distribution, etc.: 三重大学
Publication Date: 2022-09-21
Publication Date (W3CDTF): 2022-09-21
Degree grantor/type: 三重大学
Date Granted: 2022-09-21
Dissertation Number: 甲医学第2153号
Degree Type: 博士(医学)
Text Language Code: eng
Subject Heading: Pulmonary hypertension
Survival
Rats
Genome editing
Animal model
Target Audience: 一般
Note (General): application/pdf
本文/The Department of Anesthesiology and Critical Care Medicine, Mie University Graduate School of Medicine, 2‑174 Edobashi, Tsu city, Mie 514‑8507, Japan
22p
Format (IMT): application/pdf
Source: 2022DM0914 （fulltext）
https://mie-u.repo.nii.ac.jp/record/15440/files/2022DM0914.pdf
Access Restrictions: インターネット公開
Related Material (DOI): 10.1186/s12931-022-02005-w
Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）
https://irdb.nii.ac.jp
Original Data Provider (Database): 三重大学 : 三重大学学術機関リポジトリ研究成果コレクション