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文書・図像類

プライマリーCD4T同時輸注によるCEAを標的としたCAR-T療法の増強と機序

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プライマリーCD4T同時輸注によるCEAを標的としたCAR-T療法の増強と機序

Material type
文書・図像類
Author
王, 立楠ほか
Publisher
三重大学
Publication date
2022-05-27
Material Format
Digital
Capacity, size, etc.
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Note (General):

application/pdf2019年度~2021年度科学研究費補助金(基盤研究(C))研究成果報告書19K09195

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Summary, etc.:

近年 CD19を標的とした造血器腫瘍の治療において、顕著な治療効果が認められた上に、臨床応用が行われている。しかしながら、固形がんに対してCAR-T細胞療法は有効性と安全性は不明である。我々は重度免疫不全マウスを用いて、がん抗原特異的キメラ抗原受容体遺伝子を導入したT細胞を用いたがんに対するT細胞輸...

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Digital

Material Type
文書・図像類
Author/Editor
王, 立楠
加藤, 琢磨
Publication, Distribution, etc.
Publication Date
2022-05-27
Publication Date (W3CDTF)
2022-05-27
Alternative Title
Augmentation and mechanism of CAR-T cell therapy by naive CD4+ T cell help
Text Language Code
jpn